Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | protein kinase 2, putative | 0.0085 | 0.1008 | 0.4453 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0082 | 0.0949 | 0.2141 |
Entamoeba histolytica | protein kinase, putative | 0.0127 | 0.2057 | 0.909 |
Brugia malayi | Protein kinase domain containing protein | 0.0135 | 0.2263 | 0.2263 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.0085 | 0.1008 | 0.5 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0082 | 0.0949 | 0.2141 |
Trichomonas vaginalis | AGC family protein kinase | 0.0135 | 0.2263 | 0.5104 |
Loa Loa (eye worm) | hypothetical protein | 0.0227 | 0.4569 | 0.4569 |
Trichomonas vaginalis | AGC family protein kinase | 0.0053 | 0.0206 | 0.0464 |
Trichomonas vaginalis | AGC family protein kinase | 0.0135 | 0.2263 | 0.5104 |
Onchocerca volvulus | Dual specificity protein kinase TTK homolog | 0.0222 | 0.4435 | 0.5 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0445 | 1 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0222 | 0.4435 | 0.4435 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0085 | 0.1008 | 0.2273 |
Trichomonas vaginalis | AGC family protein kinase | 0.0135 | 0.2263 | 0.5104 |
Schistosoma mansoni | dual specificity serine/threonine tyrosine kinase | 0.0222 | 0.4435 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0082 | 0.0949 | 0.2141 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0093 | 0.1214 | 0.0229 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0093 | 0.1214 | 0.2737 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0082 | 0.0949 | 0.2141 |
Trypanosoma cruzi | Protein kinase B | 0.0093 | 0.1214 | 0.0229 |
Echinococcus granulosus | nervana 2 | 0.0082 | 0.0949 | 0.2141 |
Toxoplasma gondii | AGC kinase | 0.0127 | 0.2057 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0135 | 0.2263 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0135 | 0.2263 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0135 | 0.2263 | 0.5104 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0127 | 0.2057 | 0.2057 |
Trichomonas vaginalis | AGC family protein kinase | 0.0135 | 0.2263 | 0.5104 |
Loa Loa (eye worm) | TTK protein kinase | 0.0222 | 0.4435 | 0.4435 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.0085 | 0.1008 | 0.5 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0093 | 0.1214 | 0.5363 |
Echinococcus multilocularis | dual specificity serine:threonine tyrosine | 0.0222 | 0.4435 | 1 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0082 | 0.0949 | 0.2141 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0085 | 0.1008 | 0.2273 |
Trichomonas vaginalis | AGC family protein kinase | 0.0135 | 0.2263 | 0.5104 |
Echinococcus granulosus | dual specificity serine:threonine tyrosine | 0.0222 | 0.4435 | 1 |
Giardia lamblia | Kinase, TTK | 0.0222 | 0.4435 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0135 | 0.2263 | 0.5104 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0222 | 0.4435 | 1 |
Echinococcus granulosus | nervana 2 | 0.0082 | 0.0949 | 0.2141 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0093 | 0.1214 | 0.5363 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0093 | 0.1214 | 0.2737 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0127 | 0.2057 | 0.2057 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0445 | 1 | 1 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0085 | 0.1008 | 0.2273 |
Echinococcus multilocularis | nervana 2 | 0.0082 | 0.0949 | 0.2141 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0445 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0445 | 1 | 1 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0093 | 0.1214 | 0.2737 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0135 | 0.2263 | 0.2263 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0222 | 0.4435 | 1 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0093 | 0.1214 | 0.2737 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.