Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | prolyl oligopeptidase family protein | 0.0558 | 0.0823 | 0.0823 |
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.0762 | 0.1152 | 0.0359 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.0762 | 0.1152 | 0.0359 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0558 | 0.0823 | 0.5 |
Brugia malayi | hypothetical protein | 0.181 | 0.2847 | 0.2847 |
Mycobacterium tuberculosis | Probable peptidase | 0.0558 | 0.0823 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0558 | 0.0823 | 0.5 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.2368 | 0.3749 | 1 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.6234 | 1 | 1 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.2759 | 0.4382 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0558 | 0.0823 | 0.0823 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0558 | 0.0823 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0558 | 0.0823 | 0.0823 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.6234 | 1 | 1 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0558 | 0.0823 | 0.5 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.2759 | 0.4382 | 1 |
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.0762 | 0.1152 | 0.0359 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.6234 | 1 | 1 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.2759 | 0.4382 | 0.3878 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.6234 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0558 | 0.0823 | 0.0823 |
Mycobacterium tuberculosis | Probable protease II PtrBb [second part] (oligopeptidase B) | 0.0558 | 0.0823 | 0.5 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0558 | 0.0823 | 0.0823 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0558 | 0.0823 | 0.5 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0558 | 0.0823 | 0.5 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.2759 | 0.4382 | 0.3878 |
Loa Loa (eye worm) | hypothetical protein | 0.181 | 0.2847 | 0.2847 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.2759 | 0.4382 | 0.3878 |
Plasmodium falciparum | peptidase, putative | 0.0558 | 0.0823 | 0.5 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0558 | 0.0823 | 0.5 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0558 | 0.0823 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0558 | 0.0823 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.2759 | 0.4382 | 0.4382 |
Plasmodium vivax | hypothetical protein, conserved | 0.0558 | 0.0823 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0558 | 0.0823 | 0.0823 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0558 | 0.0823 | 0.5 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0558 | 0.0823 | 0.5 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0558 | 0.0823 | 0.5 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.2759 | 0.4382 | 1 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.6234 | 1 | 1 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.2759 | 0.4382 | 1 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0558 | 0.0823 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.2759 | 0.4382 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.095 | 0.1456 | 0.1456 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.