Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trypanosoma cruzi | metacaspase, putative | 0.0029 | 0.1025 | 0.1025 |
Onchocerca volvulus | 0.0027 | 0.086 | 0.7805 | |
Plasmodium falciparum | metacaspase-like protein | 0.0029 | 0.1025 | 1 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0029 | 0.1025 | 0.0902 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0027 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0274 | 0.0274 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0029 | 0.1025 | 0.3814 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.1025 | 0.3814 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0029 | 0.1025 | 0.0902 |
Loa Loa (eye worm) | fibroinase | 0.0027 | 0.086 | 0.0603 |
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.0029 | 0.1025 | 0.1025 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.1025 | 0.0773 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0027 | 0.086 | 0.8391 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.005 | 0.2688 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.1025 | 0.0773 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0027 | 0.086 | 0.8391 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0029 | 0.1025 | 0.1025 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0027 | 0.086 | 0.0603 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0108 | 0.7236 | 0.7236 |
Echinococcus multilocularis | caspase 2 | 0.0029 | 0.1025 | 0.1025 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.1025 | 0.3814 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0029 | 0.1025 | 0.3814 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.1025 | 0.3814 |
Onchocerca volvulus | 0.0027 | 0.086 | 0.7805 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.1025 | 0.3814 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0029 | 0.1025 | 0.3814 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.1025 | 0.3814 |
Echinococcus granulosus | caspase 3 | 0.0079 | 0.4969 | 0.4969 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0019 | 0.0274 | 0.3182 |
Echinococcus granulosus | cathepsin l1 | 0.0019 | 0.0274 | 0.0274 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0027 | 0.086 | 0.086 |
Echinococcus granulosus | cathepsin b | 0.0143 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0143 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0027 | 0.086 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.086 | 0.086 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.005 | 0.2688 | 0.2688 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0029 | 0.1025 | 0.3814 |
Echinococcus multilocularis | cysteine protease | 0.0027 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Plasmodium vivax | metacaspase 1, putative | 0.0029 | 0.1025 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0027 | 0.086 | 0.086 |
Brugia malayi | cathepsin L-like precursor | 0.0019 | 0.0274 | 0.0274 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.005 | 0.2688 | 0.2688 |
Onchocerca volvulus | Cathepsin L homolog | 0.0027 | 0.086 | 0.7805 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.0108 | 0.7236 | 0.7236 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0143 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0143 | 1 | 1 |
Toxoplasma gondii | cathepsin B | 0.005 | 0.2688 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.1025 | 0.3814 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0027 | 0.086 | 0.7805 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0274 | 0.1018 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.005 | 0.2688 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0274 | 0.0274 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.1025 | 1 |
Plasmodium falciparum | metacaspase 1 | 0.0029 | 0.1025 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0027 | 0.086 | 0.0603 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0029 | 0.1025 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0027 | 0.086 | 0.0603 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Loa Loa (eye worm) | cathepsin B | 0.005 | 0.2688 | 0.2482 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0027 | 0.086 | 0.086 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0029 | 0.1025 | 0.1025 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0108 | 0.7236 | 0.7236 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0027 | 0.086 | 0.086 |
Onchocerca volvulus | 0.0027 | 0.086 | 0.7805 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Onchocerca volvulus | Cathepsin F homolog | 0.0027 | 0.086 | 0.7805 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Echinococcus granulosus | caspase 8 | 0.0029 | 0.1025 | 0.1025 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0019 | 0.0274 | 0.0274 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0108 | 0.7236 | 0.7236 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.086 | 0.0603 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0019 | 0.0274 | 0.0274 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.005 | 0.2688 | 1 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0029 | 0.1025 | 0.3814 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0029 | 0.1025 | 0.3814 |
Echinococcus granulosus | cathepsin l1 | 0.0027 | 0.086 | 0.086 |
Echinococcus multilocularis | cathepsin b | 0.0143 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.086 | 1 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0029 | 0.1025 | 0.3814 |
Trypanosoma cruzi | metacaspase, putative | 0.0029 | 0.1025 | 0.1025 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Leishmania major | metacaspase, putative | 0.0029 | 0.1025 | 0.0902 |
Onchocerca volvulus | Cathepsin L homolog | 0.0027 | 0.086 | 0.7805 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0027 | 0.086 | 0.086 |
Giardia lamblia | Cathepsin B precursor | 0.005 | 0.2688 | 0.5 |
Loa Loa (eye worm) | cysteine protease | 0.0027 | 0.086 | 0.0603 |
Echinococcus multilocularis | caspase | 0.0108 | 0.7236 | 0.7236 |
Plasmodium vivax | vivapain-2 | 0.0027 | 0.086 | 0.8391 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0029 | 0.1025 | 0.3814 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0029 | 0.1025 | 0.3814 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0029 | 0.1025 | 0.1025 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Plasmodium vivax | vivapain-2 | 0.0027 | 0.086 | 0.8391 |
Giardia lamblia | Cathepsin B precursor | 0.005 | 0.2688 | 0.5 |
Echinococcus granulosus | caspase | 0.0108 | 0.7236 | 0.7236 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0143 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0143 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0274 | 0.1018 |
Trypanosoma cruzi | metacaspase, putative | 0.0029 | 0.1025 | 0.1025 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0027 | 0.086 | 0.7805 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0143 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Giardia lamblia | Cathepsin B precursor | 0.005 | 0.2688 | 0.5 |
Trypanosoma brucei | metacaspase MCA2 | 0.0029 | 0.1025 | 0.3814 |
Echinococcus multilocularis | caspase 8 | 0.0029 | 0.1025 | 0.1025 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0027 | 0.086 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0029 | 0.1025 | 0.1025 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 1 | 1 |
Trypanosoma brucei | metacaspase | 0.0029 | 0.1025 | 0.3814 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Echinococcus multilocularis | cysteine protease | 0.0027 | 0.086 | 0.086 |
Trypanosoma brucei | metacaspase MCA3 | 0.0029 | 0.1025 | 0.3814 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0027 | 0.086 | 0.7805 | |
Echinococcus multilocularis | cathepsin b | 0.0143 | 1 | 1 |
Onchocerca volvulus | 0.0027 | 0.086 | 0.7805 | |
Trypanosoma cruzi | metacaspase, putative | 0.0029 | 0.1025 | 0.1025 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Brugia malayi | Cell death protein 3 precursor | 0.0029 | 0.1025 | 0.1025 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0027 | 0.086 | 0.8391 |
Echinococcus granulosus | caspase 2 | 0.0029 | 0.1025 | 0.1025 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Echinococcus multilocularis | caspase 3 | 0.0079 | 0.4969 | 0.4969 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0029 | 0.1025 | 0.0902 |
Trypanosoma brucei | metacaspase 5, putative | 0.0029 | 0.1025 | 0.3814 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trypanosoma brucei | Metacaspase-4 | 0.0029 | 0.1025 | 0.3814 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.0274 | 0.0274 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.