Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Dopamine receptor | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0549 | 0.0687 |
Echinococcus granulosus | fmrfamide receptor | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | hypothetical protein | 0.0009 | 0.0392 | 0.049 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0008 | 0.019 | 0.0237 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0549 | 0.0366 |
Schistosoma mansoni | hypothetical protein | 0.0009 | 0.0392 | 0.049 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0009 | 0.0392 | 0.0212 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0549 | 0.0687 |
Schistosoma mansoni | biogenic amine receptor | 0.0009 | 0.0392 | 0.049 |
Schistosoma mansoni | amine GPCR | 0.0009 | 0.0392 | 0.049 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0549 | 0.0378 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0011 | 0.0623 | 0.078 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0549 | 0.0378 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0549 | 0.0366 |
Echinococcus granulosus | serotonin receptor | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0549 | 0.0687 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0009 | 0.0392 | 0.0212 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0549 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0623 | 0.0456 |
Schistosoma mansoni | biogenic amine receptor | 0.0009 | 0.0392 | 0.049 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0549 | 0.0687 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0549 | 0.0378 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0549 | 0.0366 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0549 | 0.0687 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | jun-related protein | 0.0071 | 0.7987 | 1 |
Echinococcus granulosus | sex peptide receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | somatostatin receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0009 | 0.0392 | 0.049 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0392 | 0.049 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | G protein-coupled receptor | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0009 | 0.0392 | 0.049 |
Brugia malayi | Serotonin receptor | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0392 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Brugia malayi | putative neuropeptide receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0549 | 0.0366 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0549 | 0.0366 |
Brugia malayi | Dopamine receptor protein 1 | 0.0009 | 0.0392 | 0.0206 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0549 | 0.0215 |
Echinococcus multilocularis | sex peptide receptor | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0549 | 0.0378 |
Echinococcus granulosus | g-protein coupled receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | jun protein | 0.0087 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0549 | 0.0378 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0011 | 0.0623 | 0.0442 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0549 | 0.0366 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | myosin xvIII | 0.0009 | 0.0392 | 0.049 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0549 | 0.0366 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0549 | 0.0366 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.9705 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0549 | 0.0378 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0009 | 0.0392 | 0.0206 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0036 | 0.3665 | 1 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | G-protein coupled receptor | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Brugia malayi | hypothetical protein | 0.0068 | 0.7693 | 0.7648 |
Echinococcus granulosus | neuropeptide receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | amine GPCR | 0.0009 | 0.0392 | 0.049 |
Echinococcus granulosus | orexin receptor type 2 | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0009 | 0.0392 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0549 | 0.0378 |
Brugia malayi | G-protein coupled receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0087 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0392 | 0.0206 |
Onchocerca volvulus | 0.0068 | 0.7693 | 1 | |
Echinococcus multilocularis | jun protein | 0.0087 | 1 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0549 | 0.0366 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0549 | 0.0366 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0549 | 0.0366 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0009 | 0.0392 | 0.049 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0009 | 0.0392 | 0.0212 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0392 | 0.049 |
Echinococcus multilocularis | serotonin receptor | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0549 | 0.0366 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | neuropeptide receptor | 0.0009 | 0.0392 | 0.049 |
Brugia malayi | RE15519p | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Schistosoma mansoni | neuropeptide receptor | 0.0009 | 0.0392 | 0.049 |
Echinococcus multilocularis | g protein coupled receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0549 | 0.0366 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0549 | 0.0366 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0549 | 0.0687 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0392 | 0.049 |
Onchocerca volvulus | 0.001 | 0.0549 | 0.0215 | |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0549 | 0.0366 |
Brugia malayi | Serotonin receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0549 | 0.0366 |
Schistosoma mansoni | opsin-like receptor | 0.0009 | 0.0392 | 0.049 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0549 | 0.0366 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0549 | 0.0366 |
Brugia malayi | larval opioid receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0549 | 0.0378 |
Brugia malayi | neuropeptide F receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0549 | 0.0366 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0009 | 0.0392 | 0.049 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0009 | 0.0392 | 0.049 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0009 | 0.0392 | 0.049 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.7987 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0036 | 0.3665 | 1 |
Schistosoma mansoni | amine GPCR | 0.0009 | 0.0392 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0549 | 0.0378 |
Echinococcus multilocularis | neuropeptide receptor | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0392 | 0.049 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0549 | 0.0366 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0008 | 0.019 | 0.0237 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0549 | 0.0366 |
Brugia malayi | neuropeptide F receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | g protein coupled receptor | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | Melatonin receptor type 1A | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0549 | 0.0366 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0549 | 0.0687 |
Schistosoma mansoni | histamine h1 receptor | 0.0009 | 0.0392 | 0.049 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0549 | 0.0366 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0038 | 0.3975 | 0.3859 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0392 | 0.049 |
Echinococcus multilocularis | neuropeptide receptor | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0009 | 0.0392 | 0.0212 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | hypothetical protein | 0.0009 | 0.0392 | 0.049 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0009 | 0.0392 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0009 | 0.0392 | 0.0212 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0549 | 0.0366 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0549 | 0.0366 |
Brugia malayi | follicle stimulating hormone receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0549 | 0.0366 |
Echinococcus multilocularis | fmrfamide receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | hypothetical protein | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0549 | 0.0366 |
Schistosoma mansoni | amine GPCR | 0.0009 | 0.0392 | 0.049 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0549 | 0.0366 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0009 | 0.0392 | 0.0212 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0011 | 0.0623 | 0.0442 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0009 | 0.0392 | 0.049 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0009 | 0.0392 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0087 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0549 | 0.0366 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0011 | 0.0623 | 0.078 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0549 | 0.0366 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | biogenic amine receptor | 0.0009 | 0.0392 | 0.049 |
Schistosoma mansoni | opsin-like receptor | 0.0009 | 0.0392 | 0.049 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0549 | 0.0366 |
Schistosoma mansoni | amine GPCR | 0.0009 | 0.0392 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus granulosus | allatostatin A receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | g protein coupled receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus multilocularis | somatostatin receptor | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0392 | 0.049 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0008 | 0.019 | 0.0237 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0549 | 0.0366 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0011 | 0.0623 | 0.0442 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0009 | 0.0392 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0549 | 0.0378 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.3352 | 0.3323 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0042 | 0.4409 | 0.552 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0009 | 0.0392 | 0.049 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0549 | 0.0215 |
Echinococcus multilocularis | g protein coupled receptor | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | opsin-like receptor | 0.0009 | 0.0392 | 0.049 |
Schistosoma mansoni | hypothetical protein | 0.0009 | 0.0392 | 0.049 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | voltage gated potassium channel | 0.0011 | 0.0623 | 0.0442 |
Brugia malayi | AKH receptor | 0.0009 | 0.0392 | 0.0206 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0549 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0549 | 0.0366 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0549 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0549 | 0.0378 |
Echinococcus multilocularis | fmrfamide receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | neuropeptide receptor | 0.0009 | 0.0392 | 0.049 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0009 | 0.0392 | 0.0212 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0009 | 0.0392 | 0.049 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0009 | 0.0392 | 0.049 |
Brugia malayi | GnHR receptor homolog | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | g protein coupled receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | neuropeptide receptor | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0549 | 0.0378 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0038 | 0.3975 | 0.3859 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0009 | 0.0392 | 0.0212 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0009 | 0.0392 | 0.0212 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0009 | 0.0392 | 0.049 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0038 | 0.3975 | 0.3859 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0549 | 0.0366 |
Echinococcus granulosus | g protein coupled receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0011 | 0.0623 | 0.0442 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0549 | 0.0366 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0549 | 0.0687 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0009 | 0.0392 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Brugia malayi | ORL1-like opioid receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | serotonin receptor | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0549 | 0.0366 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0042 | 0.4409 | 0.552 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Brugia malayi | Dopamine receptor protein 2 | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0549 | 0.0687 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0038 | 0.3975 | 0.3978 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0009 | 0.0392 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0392 | 0.049 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0009 | 0.0392 | 0.0212 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0549 | 0.0687 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | neuropeptide receptor | 0.0009 | 0.0392 | 0.049 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0009 | 0.0392 | 0.049 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0549 | 0.0366 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0008 | 0.019 | 0.0237 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0008 | 0.019 | 0.0237 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0009 | 0.0392 | 0.0212 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0392 | 0.049 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0549 | 0.0378 |
Echinococcus multilocularis | allatostatin A receptor | 0.0009 | 0.0392 | 0.0206 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0549 | 0.0366 |
Brugia malayi | sulfakinin receptor protein | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0009 | 0.0392 | 0.049 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0009 | 0.0392 | 0.0206 |
Echinococcus granulosus | neuropeptide s receptor | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0392 | 0.0206 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0009 | 0.0392 | 0.0206 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0549 | 0.0687 |
Schistosoma mansoni | adenoreceptor | 0.0009 | 0.0392 | 0.049 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0009 | 0.0392 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0549 | 0.0687 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0008 | 0.019 | 0.0237 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0549 | 0.0378 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0009 | 0.0392 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0392 | 0.0212 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0549 | 0.0687 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
T/C (functional) | = 126 % | Antitumor activity against mouse L1210 cells allografted in mouse assessed as survival rate at 250 mg/kg relative to control | ChEMBL. | 671454 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.