Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Alpha-L-fucosidase family protein | 0.0313 | 0.3792 | 0.5 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.0517 | 1 | 1 |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.0313 | 0.3792 | 0.5 |
Schistosoma mansoni | alpha-l-fucosidase | 0.0313 | 0.3792 | 1 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.0517 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 172 uM | Inhibition of Agrobacterium sp. beta glucosidase using 2,4-dinitrophenyl-beta-D-glucopyranoside as substrate measured for 3 mins | ChEMBL. | 24803362 |
Ki (binding) | = 716 uM | Inhibition of human lysosomal beta-glucocerebrosidase using 2,4-dinitrophenyl-beta-D-glucopyranoside as substrate by UV spectrophotometric analysis | ChEMBL. | 24803362 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.