Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | expressed conserved protein | 0.0097 | 0.1229 | 0.1622 |
Echinococcus granulosus | hypothetical protein | 0.0097 | 0.1229 | 0.1622 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0 | 0.5 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0034 | 0 | 0.5 |
Echinococcus granulosus | neutral sphingomyelinase | 0.01 | 0.1292 | 0.1704 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0191 | 0.3072 | 0.5 |
Mycobacterium ulcerans | hydrolase/amidase | 0.0285 | 0.4921 | 1 |
Schistosoma mansoni | neutral sphingomyelinase | 0.01 | 0.1292 | 0.1704 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.0421 | 0.758 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0034 | 0 | 0.5 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.0421 | 0.758 | 1 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.0421 | 0.758 | 0.758 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0421 | 0.758 | 1 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0421 | 0.758 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0 | 0.5 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0034 | 0 | 0.5 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0034 | 0 | 0.5 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0 | 0.5 |
Echinococcus multilocularis | neutral sphingomyelinase | 0.01 | 0.1292 | 0.1704 |
Loa Loa (eye worm) | hypothetical protein | 0.0545 | 1 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1292 | 0.1292 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.01 | 0.1292 | 0.1292 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0034 | 0 | 0.5 |
Echinococcus granulosus | expressed conserved protein | 0.0097 | 0.1229 | 0.1622 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0097 | 0.1229 | 0.1622 |
Brugia malayi | Ceramide glucosyltransferase | 0.0421 | 0.758 | 0.758 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0034 | 0 | 0.5 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.0421 | 0.758 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.