Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.033 | 0.1388 | 0.1388 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0645 | 0.2804 | 0.2804 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0057 | 0.0164 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0153 | 0.0153 |
Echinococcus multilocularis | calpain family protein 1, d | 0.004 | 0.0088 | 0.0088 |
Echinococcus multilocularis | calpain A | 0.0057 | 0.0164 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0088 | 0.0088 |
Echinococcus granulosus | vesicular acetylcholine transporter | 0.2247 | 1 | 1 |
Echinococcus granulosus | calpain A | 0.0057 | 0.0164 | 0.0164 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0057 | 0.0164 | 0.0164 |
Brugia malayi | calpain family protein 1 | 0.0055 | 0.0153 | 0.0153 |
Loa Loa (eye worm) | calpain family protein 1 | 0.004 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0055 | 0.0153 | 0.0153 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0057 | 0.0164 | 0.0164 |
Onchocerca volvulus | Vesicular acetylcholine transporter homolog | 0.2247 | 1 | 1 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0645 | 0.2804 | 1 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0057 | 0.0164 | 0.0164 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0055 | 0.0153 | 0.0153 |
Schistosoma mansoni | vesicular acetylcholine transporter | 0.2247 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.006 | 0.006 |
Brugia malayi | calpain family protein 1 | 0.0055 | 0.0153 | 0.0153 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0645 | 0.2804 | 1 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0645 | 0.2804 | 1 |
Plasmodium vivax | calpain, putative | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | vesicular acetylcholine transporter unc-17 | 0.2247 | 1 | 1 |
Echinococcus multilocularis | vesicular acetylcholine transporter | 0.2247 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0645 | 0.2804 | 0.2804 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.