Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | Metabotropic glutamate receptor 5 | Starlite/ChEMBL | No references |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | aldo keto reductase | 0.1313 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1313 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1313 | 1 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.1313 | 1 | 1 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.038 | 0.2765 | 0.2622 |
Leishmania major | aldo-keto reductase-like protein | 0.1313 | 1 | 1 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.006 | 0.0282 | 0.0151 |
Mycobacterium ulcerans | oxidoreductase | 0.1313 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1313 | 1 | 1 |
Echinococcus granulosus | aldehyde reductase | 0.0933 | 0.705 | 0.701 |
Giardia lamblia | Aldose reductase | 0.1313 | 1 | 0.5 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.038 | 0.2765 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1313 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1313 | 1 | 1 |
Trypanosoma cruzi | aldo-keto reductase | 0.1313 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1313 | 1 | 1 |
Schistosoma mansoni | potassium channel beta | 0.038 | 0.2765 | 0.2765 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.1313 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1313 | 1 | 1 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.006 | 0.0282 | 0.0151 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0933 | 0.705 | 0.5922 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1313 | 1 | 1 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.038 | 0.2765 | 0.5 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.038 | 0.2765 | 0.2668 |
Leishmania major | prostaglandin f synthase, putative | 0.1313 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.1313 | 1 | 1 |
Schistosoma mansoni | pol-related | 0.1313 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.1313 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1313 | 1 | 1 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0041 | 0.0133 | 0.0133 |
Trypanosoma brucei | prostaglandin f synthase | 0.1313 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1313 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1313 | 1 | 1 |
Brugia malayi | NADH-dependent xylose reductase | 0.038 | 0.2765 | 0.2765 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1313 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1313 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1313 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.1313 | 1 | 1 |
Onchocerca volvulus | 0.1313 | 1 | 1 | |
Plasmodium vivax | aldehyde reductase, putative | 0.038 | 0.2765 | 0.5 |
Onchocerca volvulus | 0.1313 | 1 | 1 | |
Loa Loa (eye worm) | oxidoreductase | 0.1313 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.1313 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.1313 | 1 | 1 |
Onchocerca volvulus | 0.1313 | 1 | 1 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1313 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1313 | 1 | 1 |
Onchocerca volvulus | 0.1313 | 1 | 1 | |
Echinococcus granulosus | aldo keto reductase | 0.1313 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1313 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.1313 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1313 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.1313 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.1313 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1313 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1313 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1313 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1313 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.1313 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.1313 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.1313 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.1313 | 1 | 1 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.1313 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1313 | 1 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.1313 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1313 | 1 | 1 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0044 | 0.0159 | 0.0159 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0049 | 0.0194 | 0.0194 |
Entamoeba histolytica | aldose reductase, putative | 0.1313 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.038 | 0.2765 | 0.2668 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.1313 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.1313 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.1313 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.1313 | 1 | 1 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.038 | 0.2765 | 0.2668 |
Echinococcus multilocularis | aldo keto reductase | 0.1313 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1313 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.1313 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1313 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1313 | 1 | 1 |
Onchocerca volvulus | 0.1313 | 1 | 1 | |
Plasmodium falciparum | aldehyde reductase, putative | 0.038 | 0.2765 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.1313 | 1 | 1 |
Echinococcus multilocularis | aldehyde reductase | 0.0933 | 0.705 | 0.701 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1313 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.1313 | 1 | 1 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.1313 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.1313 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0282 | 0.0089 |
Echinococcus granulosus | aldo keto reductase | 0.1313 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.1313 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.1313 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1313 | 1 | 1 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0056 | 0.0246 | 0.0246 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.1313 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.1313 | 1 | 1 |
Onchocerca volvulus | 0.1313 | 1 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1313 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.1313 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.1313 | 1 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.1313 | 1 | 1 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.038 | 0.2765 | 0.2765 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.