Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | melanocortin 4 receptor | Starlite/ChEMBL | No references |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | methionyl-tRNA synthetase | 0.0062 | 1 | 1 |
Giardia lamblia | Methionyl-tRNA synthetase | 0.0062 | 1 | 0.5 |
Schistosoma mansoni | methionine-tRNA synthetase | 0.0062 | 1 | 1 |
Echinococcus multilocularis | methionine tRNA synthetase | 0.0062 | 1 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0.7556 | 0.7546 |
Toxoplasma gondii | methionyl-tRNA synthetase | 0.0062 | 1 | 0.5 |
Trypanosoma brucei | methionyl-tRNA synthetase, putative | 0.0062 | 1 | 0.5 |
Trypanosoma cruzi | methionyl-tRNA synthetase, putative | 0.0062 | 1 | 0.5 |
Plasmodium vivax | methionine--tRNA ligase, putative | 0.0062 | 1 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 0.7556 | 0.7556 |
Leishmania major | methionyl-tRNA synthetase, putative | 0.0062 | 1 | 0.5 |
Echinococcus granulosus | methionine tRNA synthetase | 0.0062 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.7556 | 0.7556 |
Trichomonas vaginalis | methionine-tRNA synthetase, putative | 0.0062 | 1 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0056 | 0.7556 | 0.7546 |
Wolbachia endosymbiont of Brugia malayi | methionyl-tRNA synthetase | 0.0062 | 1 | 0.5 |
Mycobacterium leprae | Probable methionyl-tRNA synthase MetS | 0.0062 | 1 | 0.5 |
Mycobacterium tuberculosis | Methionyl-tRNA synthetase MetS (MetRS) (methionine--tRNA ligase) | 0.0062 | 1 | 0.5 |
Plasmodium falciparum | methionine--tRNA ligase | 0.0062 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.004 | 0.004 |
Onchocerca volvulus | 0.0038 | 0 | 0.5 | |
Mycobacterium ulcerans | methionyl-tRNA synthetase | 0.0062 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.