Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | beta-hexosaminidase B, putative | 0.0135 | 0.027 | 0.5 |
Echinococcus multilocularis | bifunctional protein NCOAT | 0.1463 | 1 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 20 | 0.0216 | 0.0865 | 0.0865 |
Schistosoma mansoni | aminopeptidase P homologue (M24 family) | 0.1463 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0622 | 0.3835 | 0.3835 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, alpha subunit | 0.0216 | 0.0865 | 0.5 |
Brugia malayi | Glycosyl hydrolase family 20, catalytic domain containing protein | 0.0216 | 0.0865 | 0.0865 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, putative | 0.0216 | 0.0865 | 0.5 |
Schistosoma mansoni | beta-hexosaminidase B | 0.0216 | 0.0865 | 0.0865 |
Echinococcus multilocularis | beta hexosaminidase subunit beta | 0.0216 | 0.0865 | 0.0865 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0135 | 0.027 | 0.5 |
Schistosoma mansoni | Hyaluronidase | 0.1463 | 1 | 1 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0135 | 0.027 | 0.5 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, beta subunit | 0.0216 | 0.0865 | 0.5 |
Leishmania major | glycosyl hydrolase-like protein | 0.0098 | 0 | 0.5 |
Trypanosoma brucei | endo-beta-N-acetylglucosaminidase, putative | 0.0098 | 0 | 0.5 |
Schistosoma mansoni | beta-hexosaminidase B | 0.0216 | 0.0865 | 0.0865 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, putative | 0.0216 | 0.0865 | 0.5 |
Trypanosoma cruzi | endo-beta-N-acetylglucosaminidase, putative | 0.0098 | 0 | 0.5 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0135 | 0.027 | 0.5 |
Echinococcus granulosus | beta hexosaminidase subunit beta | 0.0216 | 0.0865 | 0.0865 |
Echinococcus granulosus | bifunctional protein NCOAT | 0.1463 | 1 | 1 |
Trypanosoma cruzi | endo-beta-N-acetylglucosaminidase, putative | 0.0098 | 0 | 0.5 |
Loa Loa (eye worm) | hyaluronidase | 0.1463 | 1 | 1 |
Echinococcus multilocularis | beta hexosaminidase subunit alpha | 0.0135 | 0.027 | 0.027 |
Echinococcus granulosus | beta hexosaminidase subunit alpha | 0.0135 | 0.027 | 0.027 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.