Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.1262 | 1 | 0.5 |
Echinococcus granulosus | carbonic anhydrase II | 0.1262 | 1 | 1 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.1262 | 1 | 1 |
Echinococcus multilocularis | carbonic anhydrase II | 0.1262 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0971 | 0.7614 | 1 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.1262 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0971 | 0.7614 | 1 |
Schistosoma mansoni | carbonic anhydrase | 0.0928 | 0.7261 | 0.5671 |
Mycobacterium tuberculosis | Probable conserved transmembrane protein | 0.0151 | 0.0885 | 0.1835 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.1262 | 1 | 1 |
Plasmodium falciparum | carbonic anhydrase | 0.0491 | 0.3672 | 0.5 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.1262 | 1 | 0.5 |
Mycobacterium ulcerans | carbonic anhydrase | 0.0928 | 0.7261 | 0.9536 |
Onchocerca volvulus | 0.0131 | 0.0719 | 1 | |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.1262 | 1 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.1262 | 1 | 1 |
Echinococcus granulosus | carbonic anhydrase | 0.0491 | 0.3672 | 0.3664 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.0581 | 0.4409 | 0.9256 |
Toxoplasma gondii | hypothetical protein | 0.0491 | 0.3672 | 0.5 |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.0499 | 0.3737 | 0.7843 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase | 0.0624 | 0.4762 | 1 |
Onchocerca volvulus | Putative sulfate transporter | 0.0131 | 0.0719 | 1 |
Mycobacterium leprae | Probable transmembrane transport protein | 0.0151 | 0.0885 | 0.1219 |
Leishmania major | carbonic anhydrase-like protein | 0.1262 | 1 | 1 |
Entamoeba histolytica | carbonic anhydrase, putative | 0.0928 | 0.7261 | 1 |
Wolbachia endosymbiont of Brugia malayi | N-acetylglucosamine-1-phosphate uridyltransferase | 0.0045 | 0.0014 | 0.5 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.0928 | 0.7261 | 1 |
Echinococcus granulosus | carbonic anhydrase | 0.0491 | 0.3672 | 0.3664 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.1262 | 1 | 1 |
Mycobacterium ulcerans | carbonic anhydrase | 0.0971 | 0.7614 | 1 |
Echinococcus granulosus | carbonic anhydrase | 0.0491 | 0.3672 | 0.3664 |
Wolbachia endosymbiont of Brugia malayi | 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase | 0.0045 | 0.0014 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1249 | 0.9895 | 0.9834 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.