Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | carbonic anhydrase, putative | 0.1749 | 0.8017 | 1 |
Schistosoma mansoni | carbonic anhydrase | 0.1749 | 0.8017 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.183 | 0.8406 | 1 |
Mycobacterium ulcerans | carbonic anhydrase | 0.1749 | 0.8017 | 0.9536 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.1735 | 0.7951 | 0.9867 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.1735 | 0.7951 | 1 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.1735 | 0.7951 | 0.9867 |
Mycobacterium tuberculosis | Probable conserved transmembrane protein | 0.0285 | 0.0977 | 0.1835 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1735 | 0.7951 | 1 |
Leishmania major | carbonic anhydrase family protein, putative | 0.1749 | 0.8017 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.1735 | 0.7951 | 0.5 |
Plasmodium falciparum | carbonic anhydrase | 0.0732 | 0.3129 | 0.5 |
Echinococcus granulosus | carbonic anhydrase II | 0.1735 | 0.7951 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.183 | 0.8406 | 1 |
Onchocerca volvulus | 0.0247 | 0.0793 | 1 | |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.1094 | 0.4868 | 0.9256 |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.094 | 0.4126 | 0.7843 |
Toxoplasma gondii | hypothetical protein | 0.0732 | 0.3129 | 0.5 |
Echinococcus granulosus | carbonic anhydrase | 0.0732 | 0.3129 | 0.3924 |
Mycobacterium ulcerans | carbonic anhydrase | 0.183 | 0.8406 | 1 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase | 0.1175 | 0.5257 | 1 |
Onchocerca volvulus | Putative sulfate transporter | 0.0247 | 0.0793 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.1735 | 0.7951 | 0.7018 |
Mycobacterium leprae | Probable transmembrane transport protein | 0.0285 | 0.0977 | 0.1219 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.1735 | 0.7951 | 0.5 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.1749 | 0.8017 | 1 |
Echinococcus granulosus | carbonic anhydrase | 0.0732 | 0.3129 | 0.3924 |
Wolbachia endosymbiont of Brugia malayi | N-acetylglucosamine-1-phosphate uridyltransferase | 0.0085 | 0.0016 | 0.5 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.1735 | 0.7951 | 0.5 |
Echinococcus granulosus | carbonic anhydrase | 0.0732 | 0.3129 | 0.3924 |
Echinococcus multilocularis | carbonic anhydrase II | 0.1735 | 0.7951 | 1 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.1735 | 0.7951 | 0.7018 |
Wolbachia endosymbiont of Brugia malayi | 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase | 0.0085 | 0.0016 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.