Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0133 | 0.0271 | 0.0271 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0133 | 0.0271 | 0.0271 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0133 | 0.0271 | 0.0277 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0133 | 0.0271 | 0.0271 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0133 | 0.0271 | 0.0271 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0133 | 0.0271 | 0.0277 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0133 | 0.0271 | 0.0277 |
Echinococcus granulosus | geminin | 0.0205 | 0.1018 | 0.0768 |
Schistosoma mansoni | nuclear hormone receptor | 0.0133 | 0.0271 | 0.0271 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.1001 | 0.9275 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0133 | 0.0271 | 0.0277 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0133 | 0.0271 | 0.0277 |
Brugia malayi | ecdysteroid receptor | 0.1048 | 0.9757 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0133 | 0.0271 | 0.0277 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0133 | 0.0271 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0271 | 0.0277 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0133 | 0.0271 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0271 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0271 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.1048 | 0.9757 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.1048 | 0.9757 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0133 | 0.0271 | 0.0277 |
Schistosoma mansoni | thyroid hormone receptor | 0.0133 | 0.0271 | 0.0271 |
Echinococcus multilocularis | geminin | 0.0205 | 0.1018 | 0.083 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0133 | 0.0271 | 0.0277 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0133 | 0.0271 | 0.0277 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0133 | 0.0271 | 0.0277 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0133 | 0.0271 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0271 | 0.0277 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0133 | 0.0271 | 0.0277 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0133 | 0.0271 | 0.0277 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0133 | 0.0271 | 0.0277 |
Schistosoma mansoni | thyroid hormone receptor | 0.0133 | 0.0271 | 0.0271 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0133 | 0.0271 | 0.0277 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0133 | 0.0271 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0271 | 0.0277 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0133 | 0.0271 | 0.0277 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0133 | 0.0271 | 0.0277 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0133 | 0.0271 | 0.0271 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0133 | 0.0271 | 0.0271 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0133 | 0.0271 | 0.0277 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0133 | 0.0271 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0271 | 0.0277 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.1071 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.1018 | 0.1018 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0133 | 0.0271 | 0.0277 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0133 | 0.0271 | 0.0277 |
Brugia malayi | nuclear receptor NHR-88 | 0.0133 | 0.0271 | 0.0277 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0133 | 0.0271 | 0.0277 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.1018 | 0.1018 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0271 | 0.0277 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0133 | 0.0271 | 0.0277 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0133 | 0.0271 | 0.0271 |
Schistosoma mansoni | coup transcription factor | 0.0133 | 0.0271 | 0.0271 |
Brugia malayi | steroid hormone receptor | 0.0133 | 0.0271 | 0.0277 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.