Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | organic anion transporting polypeptide 30B | 0.0101 | 0 | 0.5 |
Echinococcus granulosus | organic anion transporting polypeptide 30B | 0.0101 | 0 | 0.5 |
Schistosoma mansoni | organic anion transporter | 0.0101 | 0 | 0.5 |
Echinococcus granulosus | Solute carrier organic anion transporter family | 0.0101 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.153 | 1 | 1 |
Schistosoma mansoni | organic anion transporter | 0.0101 | 0 | 0.5 |
Toxoplasma gondii | transporter, major facilitator family protein | 0.0101 | 0 | 0.5 |
Onchocerca volvulus | Putative organic anion transporter | 0.153 | 1 | 1 |
Trypanosoma cruzi | MFS transporter, putative | 0.0101 | 0 | 0.5 |
Echinococcus multilocularis | Solute carrier organic anion transporter family | 0.0101 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.