Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | farnesyltransferase beta subunit, putative | 0.0587 | 0.8607 | 1 |
Leishmania major | farnesyltransferase beta subunit | 0.0587 | 0.8607 | 1 |
Brugia malayi | Ras protein let-60 | 0.06 | 0.893 | 1 |
Toxoplasma gondii | prenyltransferase and squalene oxidase repeat-containing protein | 0.0587 | 0.8607 | 0.5 |
Trichomonas vaginalis | rap1 and, putative | 0.06 | 0.893 | 1 |
Entamoeba histolytica | Ras family GTPase | 0.06 | 0.893 | 1 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.0587 | 0.8607 | 0.8607 |
Entamoeba histolytica | Ras family GTPase | 0.06 | 0.893 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.06 | 0.893 | 1 |
Plasmodium falciparum | protein farnesyltransferase subunit beta | 0.0587 | 0.8607 | 0.5 |
Schistosoma mansoni | protein farnesyltransferase subunit beta | 0.0587 | 0.8607 | 0.5 |
Entamoeba histolytica | protein farnesyltransferase beta subunit, putative | 0.0587 | 0.8607 | 0.9639 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.0587 | 0.8607 | 0.8607 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.0644 | 1 | 1 |
Trypanosoma brucei | lanosterol synthase | 0.0644 | 1 | 1 |
Trichomonas vaginalis | ral, putative | 0.06 | 0.893 | 1 |
Trichomonas vaginalis | dexras1, putative | 0.06 | 0.893 | 1 |
Echinococcus multilocularis | ras gtpase | 0.06 | 0.893 | 1 |
Giardia lamblia | Prenyltransferase | 0.0587 | 0.8607 | 0.5 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.0644 | 1 | 1 |
Entamoeba histolytica | ras-1, putative | 0.06 | 0.893 | 1 |
Trichomonas vaginalis | GTP-binding protein rit, putative | 0.06 | 0.893 | 1 |
Loa Loa (eye worm) | Ras protein let-60 | 0.06 | 0.893 | 1 |
Trichomonas vaginalis | ras-dva small GTPase, putative | 0.06 | 0.893 | 1 |
Trichomonas vaginalis | rheb, putative | 0.06 | 0.893 | 1 |
Echinococcus granulosus | ras gtpase | 0.06 | 0.893 | 1 |
Brugia malayi | Ras-related protein R-Ras2 | 0.06 | 0.893 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.