Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | bacterioferrin (TpF1) | 0.0006 | 0 | 0.5 |
Onchocerca volvulus | 0.0069 | 1 | 0.5 | |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0042 | 0.5729 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0042 | 0.5729 | 1 |
Trichomonas vaginalis | lipase containing protein, putative | 0.0069 | 1 | 1 |
Trichomonas vaginalis | lipase containing protein, putative | 0.0069 | 1 | 1 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0042 | 0.5729 | 0.5729 |
Trypanosoma brucei | lipase domain protein, putative | 0.0069 | 1 | 0.5 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0006 | 0 | 0.5 |
Echinococcus granulosus | sn1 specific diacylglycerol lipase beta | 0.0069 | 1 | 1 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0042 | 0.5729 | 1 |
Loa Loa (eye worm) | lipase | 0.0069 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0069 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0042 | 0.5729 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0069 | 1 | 0.5 |
Trypanosoma brucei | lipase domain protein, putative | 0.0069 | 1 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0069 | 1 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0006 | 0 | 0.5 |
Echinococcus multilocularis | sn1 specific diacylglycerol lipase beta | 0.0069 | 1 | 1 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0042 | 0.5729 | 0.5729 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.