Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1057 | 0.6794 | 1 |
Giardia lamblia | Beta tubulin | 0.0025 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1544 | 1 | 1 |
Entamoeba histolytica | carbonic anhydrase, putative | 0.1475 | 0.955 | 1 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.1475 | 0.955 | 1 |
Echinococcus multilocularis | carbonic anhydrase II | 0.1057 | 0.6794 | 1 |
Giardia lamblia | Beta tubulin | 0.0025 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0481 | 0.3007 | 0.4426 |
Schistosoma mansoni | carbonic anhydrase | 0.0481 | 0.3007 | 0.3148 |
Trypanosoma cruzi | Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative | 0.0033 | 0.0056 | 0.0083 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.1057 | 0.6794 | 0.7114 |
Leishmania major | carbonic anhydrase-like protein | 0.1057 | 0.6794 | 0.7114 |
Echinococcus granulosus | carbonic anhydrase II | 0.1057 | 0.6794 | 1 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0481 | 0.3007 | 0.3148 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.1057 | 0.6794 | 0.7114 |
Loa Loa (eye worm) | hypothetical protein | 0.0805 | 0.5137 | 0.7561 |
Plasmodium falciparum | carbonic anhydrase | 0.0481 | 0.3007 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0481 | 0.3007 | 0.4426 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.1057 | 0.6794 | 1 |
Echinococcus multilocularis | carbonic anhydrase | 0.0481 | 0.3007 | 0.4426 |
Leishmania major | carbonic anhydrase family protein, putative | 0.1475 | 0.955 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0481 | 0.3007 | 0.4426 |
Schistosoma mansoni | carbonic anhydrase | 0.1475 | 0.955 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0481 | 0.3007 | 1 |
Brugia malayi | solute carrier family 40, member 1 | 0.0805 | 0.5137 | 0.7561 |
Trypanosoma cruzi | Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative | 0.0033 | 0.0056 | 0.0083 |
Echinococcus multilocularis | carbonic anhydrase | 0.0481 | 0.3007 | 0.4426 |
Echinococcus granulosus | carbonic anhydrase | 0.0481 | 0.3007 | 0.4426 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.0923 | 0.5913 | 0.9089 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0481 | 0.3007 | 0.4426 |
Onchocerca volvulus | 0.0805 | 0.5137 | 1 | |
Echinococcus granulosus | carbonic anhydrase | 0.0481 | 0.3007 | 0.4426 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0481 | 0.3007 | 0.4426 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1544 | 1 | 1 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0481 | 0.3007 | 0.3148 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0481 | 0.3007 | 0.4426 |
Plasmodium falciparum | inorganic anion exchanger, inorganic anion antiporter | 0.0033 | 0.0056 | 0.0187 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase | 0.0991 | 0.6363 | 1 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0481 | 0.3007 | 0.3148 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.1057 | 0.6794 | 1 |
Giardia lamblia | Beta tubulin | 0.0025 | 0 | 0.5 |
Echinococcus multilocularis | carbonic anhydrase | 0.0481 | 0.3007 | 0.4426 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.1057 | 0.6794 | 1 |
Echinococcus granulosus | carbonic anhydrase | 0.0481 | 0.3007 | 0.4426 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.1057 | 0.6794 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0481 | 0.3007 | 0.3148 |
Plasmodium vivax | sulfate transporter, putative | 0.0033 | 0.0056 | 1 |
Chlamydia trachomatis | sulfate transporter | 0.0033 | 0.0056 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0481 | 0.3007 | 0.4426 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.1057 | 0.6794 | 1 |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.0793 | 0.5057 | 0.7358 |
Mycobacterium ulcerans | carbonic anhydrase | 0.1475 | 0.955 | 0.9547 |
Toxoplasma gondii | inorganic anion transporter, sulfate permease (SulP) family protein | 0.0033 | 0.0056 | 0.0187 |
Loa Loa (eye worm) | hypothetical protein | 0.0481 | 0.3007 | 0.4426 |
Trypanosoma brucei | Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative | 0.0033 | 0.0056 | 0.0083 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0481 | 0.3007 | 0.4426 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.1057 | 0.6794 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IA (functional) | In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor gamma-Gal4 chimeric receptor in transfected CHO-K1 cells at 10 microM | ChEMBL. | 12904063 | |
IA (functional) | Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells | ChEMBL. | 12904063 | |
IA (functional) | Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells | ChEMBL. | 12904063 | |
IA (functional) | 0 | Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells | ChEMBL. | 12904063 |
IA (functional) | 0 | In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor gamma-Gal4 chimeric receptor in transfected CHO-K1 cells at 10 microM | ChEMBL. | 12904063 |
IA (functional) | 0 | Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells | ChEMBL. | 12904063 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.