Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | glucose transporter, putative | 0.0021 | 0.0428 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0069 | 0.2529 | 1 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0069 | 0.2529 | 1 |
Trypanosoma cruzi | hexose transporter, putative | 0.0021 | 0.0428 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.0021 | 0.0428 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0021 | 0.0428 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0021 | 0.0428 | 0.5 |
Trypanosoma brucei | glucose transporter 2A | 0.0021 | 0.0428 | 0.5 |
Leishmania major | glucose transporter, lmgt3 | 0.0021 | 0.0428 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0238 | 1 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0069 | 0.2529 | 1 |
Trypanosoma cruzi | hexose transporter | 0.0021 | 0.0428 | 1 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0069 | 0.2529 | 1 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.0069 | 0.2529 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0069 | 0.2529 | 1 |
Leishmania major | glucose transporter, lmgt1 | 0.0021 | 0.0428 | 0.5 |
Trypanosoma brucei | glucose transporter 1E | 0.0021 | 0.0428 | 0.5 |
Plasmodium vivax | hexose transporter | 0.0069 | 0.2529 | 0.5 |
Leishmania major | glucose transporter/membrane transporter D2, putative | 0.0021 | 0.0428 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0021 | 0.0428 | 1 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0069 | 0.2529 | 1 |
Schistosoma mansoni | glucose transport protein | 0.0069 | 0.2529 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0021 | 0.0428 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0021 | 0.0428 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0021 | 0.0428 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0069 | 0.2529 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.0021 | 0.0428 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.2529 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0021 | 0.0428 | 1 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0021 | 0.0428 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0021 | 0.0428 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0069 | 0.2529 | 0.5 |
Leishmania major | glucose transporter, lmgt2 | 0.0021 | 0.0428 | 0.5 |
Plasmodium falciparum | hexose transporter | 0.0069 | 0.2529 | 0.5 |
Loa Loa (eye worm) | sugar transporter | 0.0069 | 0.2529 | 0.5 |
Brugia malayi | Sugar transporter family protein | 0.0069 | 0.2529 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0069 | 0.2529 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.0021 | 0.0428 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0069 | 0.2529 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0069 | 0.2529 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 0.71 uM | Inhibitory concentration against Hepatitis C virus serine protease | ChEMBL. | 15239657 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.