Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0033 | 0.0038 | 1 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | abcb9, putative | 0.0033 | 0.0038 | 0.5 |
Toxoplasma gondii | ABC transporter transmembrane region domain-containing protein | 0.0033 | 0.0038 | 0.5 |
Toxoplasma gondii | ATP-binding cassette transporter ABC.B1 | 0.0033 | 0.0038 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0038 | 0.0038 |
Entamoeba histolytica | P-glycoprotein-2 | 0.0033 | 0.0038 | 0.5 |
Leishmania major | p-glycoprotein | 0.0033 | 0.0038 | 0.5 |
Schistosoma mansoni | multidrug resistance protein | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0033 | 0.0038 | 0.5 |
Entamoeba histolytica | P-glycoprotein 5, putative | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0033 | 0.0038 | 0.5 |
Schistosoma mansoni | smdr2 | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0033 | 0.0038 | 0.5 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0033 | 0.0038 | 1 |
Trichomonas vaginalis | ABC transporter, half transporter, putative | 0.0033 | 0.0038 | 0.5 |
Brugia malayi | Fibroblast growth factor family protein | 0.006 | 0.2878 | 0.2851 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0033 | 0.0038 | 1 |
Trichomonas vaginalis | abcb9, putative | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | ABC transporter, half transporter, putative | 0.0033 | 0.0038 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0038 | 0.0038 |
Entamoeba histolytica | P-glycoprotein-2 | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | ABC transporter, putative | 0.0033 | 0.0038 | 0.5 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0033 | 0.0038 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.2878 | 0.2878 |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.0033 | 0.0038 | 1 |
Chlamydia trachomatis | ABC transporter ATP binding protein/permease | 0.0033 | 0.0038 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.2878 | 0.2878 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | ABC transporter, putative | 0.0033 | 0.0038 | 0.5 |
Mycobacterium tuberculosis | Probable transmembrane multidrug efflux pump | 0.0033 | 0.0038 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.006 | 0.2878 | 0.5 |
Entamoeba histolytica | P-glycoprotein-5 | 0.0033 | 0.0038 | 0.5 |
Plasmodium vivax | multidrug resistance protein 1, putative | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | ABC transporter, putative | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0033 | 0.0038 | 0.5 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0033 | 0.0038 | 1 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0033 | 0.0038 | 0.5 |
Loa Loa (eye worm) | ATP-binding cassette sub-family B member 2 | 0.0033 | 0.0038 | 0.0038 |
Entamoeba histolytica | P-glycoprotein-1 | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0033 | 0.0038 | 0.5 |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.0033 | 0.0038 | 1 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0033 | 0.0038 | 0.5 |
Loa Loa (eye worm) | multidrug resistance protein 3 | 0.0033 | 0.0038 | 0.0038 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0033 | 0.0038 | 1 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0033 | 0.0038 | 1 |
Plasmodium falciparum | multidrug resistance protein 1 | 0.0033 | 0.0038 | 0.5 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0033 | 0.0038 | 1 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0033 | 0.0038 | 0.5 |
Schistosoma mansoni | multidrug resistance protein | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | ABC transporter, putative | 0.0033 | 0.0038 | 0.5 |
Entamoeba histolytica | P-glyco protein 6, putative | 0.0033 | 0.0038 | 0.5 |
Schistosoma mansoni | multidrug resistance protein | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0033 | 0.0038 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 1 | 1 |
Entamoeba histolytica | P-glycoprotein-2, putative | 0.0033 | 0.0038 | 0.5 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0033 | 0.0038 | 1 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0033 | 0.0038 | 0.5 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0033 | 0.0038 | 1 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0033 | 0.0038 | 0.5 |
Leishmania major | ATP-binding cassette protein subfamily B, member 2, putative | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | taga, putative | 0.0033 | 0.0038 | 0.5 |
Brugia malayi | Fibroblast growth factor family protein | 0.006 | 0.2878 | 0.2851 |
Trichomonas vaginalis | abcb9, putative | 0.0033 | 0.0038 | 0.5 |
Onchocerca volvulus | 0.0033 | 0.0038 | 0.5 | |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0033 | 0.0038 | 1 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0033 | 0.0038 | 1 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0033 | 0.0038 | 0.5 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0033 | 0.0038 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.