Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0402 | 1 | 1 | |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0361 | 0.749 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0361 | 0.749 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0253 | 0.0687 | 0.0917 |
Trypanosoma brucei | phospholipase A1, putative | 0.0402 | 1 | 0.5 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0361 | 0.749 | 1 |
Loa Loa (eye worm) | platelet-activating factor acetylhydrolase | 0.0402 | 1 | 1 |
Trypanosoma cruzi | phospholipase A1, putative | 0.0402 | 1 | 0.5 |
Trypanosoma cruzi | phospholipase A1, putative | 0.0402 | 1 | 0.5 |
Leishmania major | phospholipase A1, putative | 0.0402 | 1 | 0.5 |
Onchocerca volvulus | 0.0402 | 1 | 1 | |
Onchocerca volvulus | 0.0402 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.