Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0181 | 1 | 1 |
Echinococcus multilocularis | protein of unknown function DUF590 | 0.0109 | 0.2643 | 0.6258 |
Echinococcus granulosus | protein of unknown function DUF590 | 0.0109 | 0.2643 | 0.6258 |
Echinococcus multilocularis | protein of unknown function DUF590 | 0.0109 | 0.2643 | 0.6258 |
Echinococcus granulosus | protein of unknown function DUF590 | 0.0109 | 0.2643 | 0.6258 |
Schistosoma mansoni | lipoxygenase | 0.0125 | 0.4223 | 0.4223 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0109 | 0.2643 | 0.2643 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0125 | 0.4223 | 1 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0125 | 0.4223 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0087 | 0.0387 | 0.0387 |
Onchocerca volvulus | 0.0088 | 0.049 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Reduction (functional) | NA 0 % | Percent reduction in area under glucose tolerance curve (AUC) was determined at 30 micromol/kg dose of diet in mice; IA = No significant activity | ChEMBL. | 7966158 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.