Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | coagulation factor II (thrombin) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0684 | 0.1665 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.03 | 0.0732 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.086 | 0.2096 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0007 | 0.0684 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0004 | 0.0092 | 0.0223 |
Brugia malayi | intermediate filament protein | 0.0007 | 0.0892 | 0.1994 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0007 | 0.0684 | 1 |
Echinococcus multilocularis | lamin | 0.0007 | 0.0892 | 0.0892 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0684 | 0.1665 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0021 | 0.4105 | 0.4105 |
Echinococcus granulosus | lamin | 0.0007 | 0.0892 | 0.0892 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0021 | 0.4105 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.03 | 0.0732 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0007 | 0.0684 | 0.5 |
Echinococcus multilocularis | lamin dm0 | 0.0007 | 0.0892 | 0.0892 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0021 | 0.4105 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0007 | 0.0684 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0684 | 0.1665 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.4105 | 0.3527 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.0684 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.0684 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.0684 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0007 | 0.0684 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0021 | 0.4105 | 0.5 |
Loa Loa (eye worm) | intermediate filament protein | 0.0007 | 0.0892 | 0.2173 |
Toxoplasma gondii | kringle domain-containing protein | 0.0021 | 0.4105 | 0.5 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0684 | 0.1475 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0684 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0007 | 0.0892 | 0.0892 |
Brugia malayi | Kringle domain containing protein | 0.0021 | 0.4105 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0007 | 0.0684 | 0.5 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0007 | 0.0892 | 0.1994 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.4105 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0007 | 0.0684 | 0.5 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0684 | 0.1475 |
Onchocerca volvulus | 0.0021 | 0.4105 | 1 | |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0007 | 0.0684 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0021 | 0.4105 | 1 |
Echinococcus multilocularis | musashi | 0.0007 | 0.0892 | 0.0892 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0684 | 0.1475 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0007 | 0.0892 | 0.2173 |
Echinococcus granulosus | lamin dm0 | 0.0007 | 0.0892 | 0.0892 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0005 | 0.03 | 0.139 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0007 | 0.0684 | 1 |
Onchocerca volvulus | 0.0007 | 0.0892 | 0.0609 | |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0005 | 0.03 | 0.5 |
Onchocerca volvulus | 0.0007 | 0.0892 | 0.0609 | |
Echinococcus multilocularis | geminin | 0.0047 | 1 | 1 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0021 | 0.4105 | 0.4105 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.03 | 0.0732 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.03 | 0.0732 |
Mycobacterium ulcerans | hypothetical protein | 0.0007 | 0.0684 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.03 | 0.0732 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0021 | 0.4105 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0007 | 0.0684 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0021 | 0.4105 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0892 | 0.2173 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.