Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | dual specificity serine/threonine tyrosine kinase | 0.0088 | 0.5642 | 0.5642 |
Loa Loa (eye worm) | TTK protein kinase | 0.0088 | 0.5642 | 0.5642 |
Echinococcus granulosus | cyclin dependent kinase | 0.0053 | 0.0084 | 0.0084 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0053 | 0.0084 | 0.0084 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0053 | 0.0084 | 0.0084 |
Brugia malayi | cell division control protein 2 homolog | 0.0053 | 0.0084 | 0.0084 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0115 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0115 | 1 | 1 |
Giardia lamblia | Kinase, CMGC CDK | 0.0053 | 0.0084 | 0.0084 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0115 | 1 | 1 |
Trypanosoma brucei | polo-like protein kinase | 0.0115 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0088 | 0.5642 | 0.5642 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0053 | 0.0084 | 0.0084 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0115 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0053 | 0.0084 | 0.0084 |
Giardia lamblia | Kinase, PLK | 0.0115 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0084 | 0.0084 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0115 | 1 | 1 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0053 | 0.0084 | 0.0084 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0053 | 0.0084 | 0.0084 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0053 | 0.0084 | 0.0084 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.0053 | 0.0084 | 0.0084 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0053 | 0.0084 | 0.0084 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0058 | 0.0751 | 0.0751 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0115 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.5642 | 0.5642 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0115 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0084 | 0.0084 |
Plasmodium vivax | protein kinase Crk2 | 0.0053 | 0.0084 | 0.5 |
Schistosoma mansoni | kinase | 0.0059 | 0.0992 | 0.0992 |
Echinococcus multilocularis | dual specificity serine:threonine tyrosine | 0.0088 | 0.5642 | 0.5642 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0053 | 0.0084 | 0.0084 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0115 | 1 | 1 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0053 | 0.0084 | 0.0084 |
Giardia lamblia | Kinase, CMGC CDK | 0.0053 | 0.0084 | 0.0084 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0053 | 0.0084 | 0.0084 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0115 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0053 | 0.0084 | 0.0084 |
Giardia lamblia | Kinase, TTK | 0.0088 | 0.5642 | 0.5642 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0115 | 1 | 1 |
Plasmodium falciparum | protein kinase 5 | 0.0053 | 0.0084 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0115 | 1 | 1 |
Echinococcus granulosus | dual specificity serine:threonine tyrosine | 0.0088 | 0.5642 | 0.5642 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0053 | 0.0084 | 0.0084 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.0053 | 0.0084 | 0.0084 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0053 | 0.0084 | 0.0084 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0115 | 1 | 1 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0053 | 0.0084 | 0.0084 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0058 | 0.0751 | 0.0751 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0115 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0053 | 0.0084 | 0.0084 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0115 | 1 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0053 | 0.0084 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0115 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0053 | 0.0084 | 0.0084 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0084 | 0.0084 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0053 | 0.0084 | 0.0084 |
Brugia malayi | Protein kinase domain containing protein | 0.0053 | 0.0084 | 0.0084 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0115 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.5642 | 0.5642 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.