Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0445 | 0.5371 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0167 | 0.0902 | 0.5 |
Brugia malayi | hypothetical protein | 0.0156 | 0.0817 | 0.9858 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0167 | 0.0902 | 0.5 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0874 | 0.6328 | 1 |
Brugia malayi | hypothetical protein | 0.0156 | 0.0817 | 0.9857 |
Mycobacterium ulcerans | carbon monoxide dehydrogenase | 0.0111 | 0.0468 | 0.042 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0156 | 0.0817 | 0.1291 |
Schistosoma mansoni | loxhd1 | 0.0156 | 0.0817 | 0.1291 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0108 | 0.0445 | 0.5371 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0156 | 0.0817 | 0.1291 |
Schistosoma mansoni | hypothetical protein | 0.0156 | 0.0817 | 0.1291 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 | 0.0079 | 0.0223 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.0817 | 0.9858 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0158 | 0.0829 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0156 | 0.0817 | 0.1291 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (large chain) | 0.0079 | 0.0223 | 0.0179 |
Onchocerca volvulus | 0.0156 | 0.0817 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.0817 | 0.9858 |
Echinococcus multilocularis | RUN | 0.0156 | 0.0817 | 0.1291 |
Loa Loa (eye worm) | doublecortin family protein | 0.0156 | 0.0817 | 0.9858 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0158 | 0.0829 | 1 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0874 | 0.6328 | 1 |
Echinococcus granulosus | RUN | 0.0156 | 0.0817 | 0.1291 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.0829 | 1 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0671 | 0.4768 | 0.7535 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0156 | 0.0817 | 0.1291 |
Brugia malayi | hypothetical protein | 0.0156 | 0.0817 | 0.9858 |
Onchocerca volvulus | 0.0156 | 0.0817 | 1 | |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0158 | 0.0829 | 1 |
Schistosoma mansoni | rab6-interacting | 0.0156 | 0.0817 | 0.1291 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0079 | 0.0223 | 0.0173 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0156 | 0.0817 | 0.1291 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0156 | 0.0817 | 0.1291 |
Schistosoma mansoni | hypothetical protein | 0.0108 | 0.0445 | 0.0703 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0156 | 0.0817 | 0.5 |
Schistosoma mansoni | polycystin 1-related | 0.0156 | 0.0817 | 0.1291 |
Schistosoma mansoni | lipoxygenase | 0.0874 | 0.6328 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0671 | 0.4768 | 0.7535 |
Schistosoma mansoni | rab6-interacting | 0.0156 | 0.0817 | 0.1291 |
Trichomonas vaginalis | aldehyde oxidase, putative | 0.0167 | 0.0902 | 0.5 |
Schistosoma mansoni | lipoxygenase | 0.0592 | 0.4167 | 0.6586 |
Brugia malayi | Doublecortin family protein | 0.0156 | 0.0817 | 0.9858 |
Mycobacterium tuberculosis | Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) | 0.1307 | 0.9657 | 1 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0156 | 0.0817 | 0.5 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0671 | 0.4768 | 0.7535 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.0817 | 0.9857 |
Mycobacterium ulcerans | mycothiol conjugate amidase Mca | 0.1352 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Rice stem length (functional) | = 2.4 cm | Compound was tested for its activity in rice stem elongation test at a concentration of 1 microM. Stem length was measured after 7 days of transplantation | ChEMBL. | 10091696 |
Rice stem length (functional) | = 2.4 cm | Compound was tested for its activity in rice stem elongation test at a concentration of 1 microM. Stem length was measured after 7 days of transplantation | ChEMBL. | 10091696 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.