Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 6.2 ug ml-1 | Antifungal activity against Trichophyton mentagrophytes. | ChEMBL. | 3510297 |
MIC (functional) | > 100 ug ml-1 | Antifungal activity against Epidermophyton floccosum. | ChEMBL. | 3510297 |
MIC (functional) | > 100 ug ml-1 | Antifungal activity against Microsporum canis | ChEMBL. | 3510297 |
MIC (functional) | > 100 ug ml-1 | Antifungal activity measured against Aspergillus fumigatus | ChEMBL. | 3510297 |
MIC (functional) | > 100 ug ml-1 | Antifungal activity measured against Sporothrix schenck ii. | ChEMBL. | 3510297 |
MIC (functional) | > 100 ug ml-1 | Antifungal activity against Candida parapsilosis. | ChEMBL. | 3510297 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.