Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.3108 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.054 | 1 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0446 | 0.7221 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.054 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0212 | 0.0319 | 0.1027 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.3108 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0446 | 0.7221 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.054 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.3108 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.3108 | 1 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.0486 | 0.8408 | 0.5 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0306 | 0.3108 | 0.0507 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.3108 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.054 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0212 | 0.0319 | 0.1027 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0306 | 0.3108 | 0.0507 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.3108 | 1 |
Onchocerca volvulus | 0.0391 | 0.5611 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 0 % | Antiallergic agent with Aldose reductase Inhibitory Activity at 10E-6 M concentration | ChEMBL. | 6779009 |
Inhibition (binding) | = 0 % | Antiallergic agent with Aldose reductase Inhibitory Activity at 10E-6 M concentration | ChEMBL. | 6779009 |
Inhibition (binding) | = 43 % | Antiallergic agent with Aldose reductase Inhibitory Activity at 10E-5 M concentration | ChEMBL. | 6779009 |
Inhibition (binding) | = 43 % | Antiallergic agent with Aldose reductase Inhibitory Activity at 10E-5 M concentration | ChEMBL. | 6779009 |
Inhibition (binding) | = 70 % | Percent inhibition of rabbit lens aldose reductase in vitro at 10E-4 M concentration | ChEMBL. | 6779009 |
Inhibition (binding) | = 70 % | Percent inhibition of rabbit lens aldose reductase in vitro at 10E-4 M concentration | ChEMBL. | 6779009 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.