Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | beta-glucosidase, putative | 0.0136 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 3.1 ug ml-1 | In vitro minimum inhibitory concentration of the compound against S. aureus 6538P using standard agar dilution method | ChEMBL. | 10782693 |
MIC (functional) | = 128 ug ml-1 | In vitro minimum inhibitory concentration of the compound against S. pyogenes PIU 2548 using standard agar dilution method | ChEMBL. | 10782693 |
MIC (functional) | > 128 ug ml-1 | In vitro minimum inhibitory concentration of the compound against S. pyogenes 930 using standard agar dilution method | ChEMBL. | 10782693 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.