Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | cell-cycle-associated protein kinase GSK, putative | 0.0058 | 0 | 0.5 |
Onchocerca volvulus | 0.0769 | 1 | 1 | |
Giardia lamblia | Kinase, CDC7 | 0.0769 | 1 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0058 | 0 | 0.5 |
Trypanosoma cruzi | glycogen synthase kinase 3, putative | 0.0058 | 0 | 0.5 |
Trypanosoma brucei | protein kinase, putative | 0.0058 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0769 | 1 | 1 |
Echinococcus multilocularis | CDC7 cell division cycle 7 | 0.0769 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0769 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0769 | 1 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0058 | 0 | 0.5 |
Onchocerca volvulus | 0.0769 | 1 | 1 | |
Echinococcus granulosus | CDC7 cell division cycle 7 | 0.0769 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0769 | 1 | 1 |
Leishmania major | glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 | 0.0058 | 0 | 0.5 |
Loa Loa (eye worm) | CDC7 protein kinase | 0.0769 | 1 | 1 |
Plasmodium vivax | glycogen synthase kinase 3, putative | 0.0058 | 0 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0058 | 0 | 0.5 |
Plasmodium falciparum | glycogen synthase kinase 3 | 0.0058 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | = 10 MU | Psychotomimetic potency expressed as the effective dose of mescaline divided by the effective dose of the compound in human | ChEMBL. | 7277405 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.