Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.126 | 0.5029 | 0.5017 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.006 | 0.0024 | 0.0049 |
Schistosoma mansoni | glucose transport protein | 0.006 | 0.0024 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0024 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.006 | 0.0024 | 0.0049 |
Onchocerca volvulus | Adenylate cyclase type 2 homolog | 0.126 | 0.5029 | 1 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.006 | 0.0024 | 0.0049 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.006 | 0.0024 | 0.0049 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.006 | 0.0024 | 0.0049 |
Plasmodium falciparum | hexose transporter | 0.006 | 0.0024 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.006 | 0.0024 | 0.5 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.006 | 0.0024 | 0.5 |
Onchocerca volvulus | Adenylate cyclase type 3 homolog | 0.126 | 0.5029 | 1 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.006 | 0.0024 | 0.0049 |
Brugia malayi | Adenylyl cyclase protein | 0.126 | 0.5029 | 1 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.006 | 0.0024 | 0.0049 |
Plasmodium vivax | hexose transporter | 0.006 | 0.0024 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.006 | 0.0024 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.1207 | 0.4805 | 0.4793 |
Trichomonas vaginalis | conserved hypothetical protein | 0.006 | 0.0024 | 0.5 |
Echinococcus granulosus | adenylate cyclase type IX | 0.1246 | 0.4971 | 0.9884 |
Echinococcus multilocularis | adenylate cyclase type IX | 0.1246 | 0.4971 | 0.9884 |
Schistosoma mansoni | glucose transport protein | 0.006 | 0.0024 | 0.5 |
Echinococcus granulosus | adenylate cyclase 9 | 0.126 | 0.5029 | 1 |
Echinococcus multilocularis | adenylate cyclase 9 | 0.126 | 0.5029 | 1 |
Onchocerca volvulus | 0.126 | 0.5029 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
T/C (functional) | = 163 | Antitumor activity of the compound administered intraperitoneally in mice implanted with P388 leukemia cells with reference to Optimum dose of anguidin(mg/kg per injection) | ChEMBL. | 4009618 |
T/C (functional) | = 181 | Antitumor activity in mice implanted with P388 leukemia cells administered intraperitoneally at a dose 16 mg/kg | ChEMBL. | 4009618 |
T/C (functional) | = 163 | Antitumor activity of the compound administered intraperitoneally in mice implanted with P388 leukemia cells with reference to Optimum dose of anguidin(mg/kg per injection) | ChEMBL. | 4009618 |
T/C (functional) | = 181 | Antitumor activity in mice implanted with P388 leukemia cells administered intraperitoneally at a dose 16 mg/kg | ChEMBL. | 4009618 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.