Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | adenosylhomocysteinase | 0.0254 | 1 | 1 |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.0254 | 1 | 0.5 |
Onchocerca volvulus | 0.0106 | 0.148 | 0.5 | |
Echinococcus granulosus | adenosylhomocysteinase | 0.0254 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0254 | 1 | 1 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.0254 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0157 | 0.4444 | 0.3479 |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.0254 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0254 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0157 | 0.4444 | 0.3479 |
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.0254 | 1 | 1 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.0254 | 1 | 1 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.0254 | 1 | 1 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0254 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0254 | 1 | 1 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.0254 | 1 | 1 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0254 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0157 | 0.4444 | 0.3479 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0157 | 0.4444 | 0.3479 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.0254 | 1 | 1 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.0254 | 1 | 1 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.0254 | 1 | 1 |
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.0254 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 132 % | Percent plasma glucose concentration of drug treated mice (ob/ob) relative to vehicle control animals | ChEMBL. | 1548684 |
Activity (functional) | = 132 % | Percent plasma glucose concentration of drug treated mice (ob/ob) relative to vehicle control animals | ChEMBL. | 1548684 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.