Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0406 | 0.5023 | 0.5023 |
Schistosoma mansoni | tyrosine kinase | 0.0128 | 0.0858 | 0.0987 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0081 | 0.0153 | 0.0153 |
Brugia malayi | SRC-1 | 0.0138 | 0.1011 | 0.2553 |
Brugia malayi | hypothetical protein | 0.0138 | 0.1011 | 0.2553 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.0138 | 0.1011 | 0.1011 |
Onchocerca volvulus | 0.0081 | 0.0153 | 0.151 | |
Echinococcus multilocularis | 0.0081 | 0.0153 | 0.0153 | |
Onchocerca volvulus | Suppressor of cytokine signaling 7 homolog | 0.0081 | 0.0153 | 0.151 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0081 | 0.0153 | 0.0153 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.0081 | 0.0153 | 0.0386 |
Schistosoma mansoni | suppressor of cytokine signaling | 0.0081 | 0.0153 | 0.0176 |
Brugia malayi | SH2 domain containing protein | 0.0081 | 0.0153 | 0.0386 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.0081 | 0.0153 | 0.0386 |
Schistosoma mansoni | tyrosine kinase | 0.0138 | 0.1011 | 0.1163 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0138 | 0.1011 | 0.1011 |
Echinococcus multilocularis | NMDA receptor | 0.0138 | 0.1012 | 0.1012 |
Schistosoma mansoni | tensin-related | 0.0081 | 0.0153 | 0.0176 |
Brugia malayi | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Schistosoma mansoni | protein kinase | 0.0128 | 0.0858 | 0.0987 |
Schistosoma mansoni | glutamate receptor kainate | 0.0335 | 0.3959 | 0.4556 |
Echinococcus granulosus | guanine nucleotide exchange factor VAV2 | 0.0081 | 0.0153 | 0.0153 |
Schistosoma mansoni | tensin | 0.0081 | 0.0153 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Schistosoma mansoni | glutamate receptor kainate | 0.0335 | 0.3959 | 0.4556 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0138 | 0.1011 | 0.2553 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0406 | 0.5023 | 0.5023 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.1011 | 0.2553 |
Brugia malayi | SH2 domain containing protein | 0.0138 | 0.1011 | 0.2553 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0138 | 0.1011 | 0.2553 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0191 | 0.1803 | 0.4554 |
Schistosoma mansoni | SH2A | 0.0081 | 0.0153 | 0.0176 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0138 | 0.1011 | 0.1011 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0406 | 0.5023 | 0.5023 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0315 | 0.3666 | 0.3666 |
Schistosoma mansoni | suppressor of cytokine signaling | 0.0081 | 0.0153 | 0.0176 |
Schistosoma mansoni | GTPase activating protein | 0.0081 | 0.0153 | 0.0176 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0081 | 0.0153 | 0.0386 |
Schistosoma mansoni | tensin-related | 0.0081 | 0.0153 | 0.0176 |
Brugia malayi | SH2 domain containing protein | 0.0081 | 0.0153 | 0.0386 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0081 | 0.0153 | 0.0386 |
Echinococcus granulosus | tyrosine kinase | 0.0138 | 0.1011 | 0.1011 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.0081 | 0.0153 | 0.0176 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0138 | 0.1011 | 0.1011 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0138 | 0.1011 | 0.2553 |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.0138 | 0.1011 | 0.1011 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0081 | 0.0153 | 0.0153 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0128 | 0.0858 | 0.2167 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0191 | 0.1803 | 0.1803 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0138 | 0.1011 | 0.1011 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0081 | 0.0153 | 0.0176 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0138 | 0.1011 | 0.1011 |
Brugia malayi | cytokine inducible SH2-containing protein 5 | 0.0081 | 0.0153 | 0.0386 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.0081 | 0.0153 | 0.0386 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0335 | 0.3959 | 0.3959 |
Schistosoma mansoni | tensin | 0.0081 | 0.0153 | 0.0176 |
Echinococcus multilocularis | SH2 motif | 0.0081 | 0.0153 | 0.0153 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0335 | 0.3959 | 0.4556 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0138 | 0.1011 | 0.1011 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0138 | 0.1011 | 0.1011 |
Onchocerca volvulus | Suppressor of cytokine signaling at 36E homolog | 0.0081 | 0.0153 | 0.151 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0138 | 0.1011 | 0.2553 |
Schistosoma mansoni | nck2/grb4 | 0.0081 | 0.0153 | 0.0176 |
Echinococcus multilocularis | tyrosine kinase | 0.0138 | 0.1011 | 0.1011 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0335 | 0.3959 | 0.4556 |
Echinococcus multilocularis | phosphatidylinositol 3 kinase regulatory subunit | 0.0081 | 0.0153 | 0.0153 |
Echinococcus multilocularis | SH2 motif | 0.0081 | 0.0153 | 0.0153 |
Echinococcus multilocularis | suppressor of cytokine signaling 7 | 0.0081 | 0.0153 | 0.0153 |
Echinococcus multilocularis | tensin | 0.0081 | 0.0153 | 0.0153 |
Chlamydia trachomatis | arginine ABC transporter substrate-binding protein ArtJ | 0.0355 | 0.4258 | 0.5 |
Echinococcus multilocularis | SH2 domain containing protein 7 | 0.0081 | 0.0153 | 0.0153 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0138 | 0.1011 | 0.1011 |
Echinococcus granulosus | tensin | 0.0081 | 0.0153 | 0.0153 |
Brugia malayi | SH2 domain containing protein | 0.0138 | 0.1011 | 0.2553 |
Schistosoma mansoni | hypothetical protein | 0.0138 | 0.1012 | 0.1165 |
Brugia malayi | SH2 domain containing protein | 0.0081 | 0.0153 | 0.0386 |
Echinococcus granulosus | glutamate receptor NMDA | 0.0244 | 0.2602 | 0.2602 |
Schistosoma mansoni | alpha-glucosidase | 0.0164 | 0.1403 | 0.1615 |
Schistosoma mansoni | glutamate receptor kainate | 0.0335 | 0.3959 | 0.4556 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0138 | 0.1011 | 0.2553 |
Brugia malayi | protein-tyrosine kinase | 0.0138 | 0.1011 | 0.2553 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0335 | 0.3959 | 1 |
Schistosoma mansoni | vav2 | 0.0081 | 0.0153 | 0.0176 |
Brugia malayi | Guanylyl cyclase protein 23 | 0.0128 | 0.0858 | 0.2167 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0493 | 0.6334 | 0.6334 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0406 | 0.5023 | 0.5023 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0081 | 0.0153 | 0.0153 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0128 | 0.0858 | 0.2167 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0081 | 0.0153 | 0.0153 |
Schistosoma mansoni | signal transduction protein lnk-related | 0.0081 | 0.0153 | 0.0176 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0335 | 0.3959 | 0.3959 |
Mycobacterium ulcerans | glutamine-binding lipoprotein GlnH | 0.0355 | 0.4258 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0138 | 0.1011 | 0.1163 |
Echinococcus granulosus | SHC transforming protein 3 | 0.0081 | 0.0153 | 0.0153 |
Brugia malayi | SH2 domain containing protein | 0.0081 | 0.0153 | 0.0386 |
Brugia malayi | Variant SH3 domain containing protein | 0.0081 | 0.0153 | 0.0386 |
Echinococcus multilocularis | SH2 domain containing adapter protein F | 0.0081 | 0.0153 | 0.0153 |
Leishmania major | extracellular receptor, putative | 0.0071 | 0 | 0.5 |
Echinococcus granulosus | glutamate receptor 2 | 0.0267 | 0.2947 | 0.2947 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0138 | 0.1011 | 0.1163 |
Echinococcus multilocularis | glutamate receptor ionotropic kainate | 0.0138 | 0.1012 | 0.1012 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0081 | 0.0153 | 0.0176 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0138 | 0.1011 | 0.2553 |
Schistosoma mansoni | tyrosine kinase | 0.0138 | 0.1011 | 0.1163 |
Schistosoma mansoni | alpha-glucosidase | 0.0164 | 0.1403 | 0.1615 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0138 | 0.1011 | 0.2553 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0081 | 0.0153 | 0.0386 |
Brugia malayi | SH2 domain containing protein | 0.0081 | 0.0153 | 0.0386 |
Echinococcus granulosus | c src tyrosine kinase | 0.0138 | 0.1011 | 0.1011 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0128 | 0.0858 | 0.2167 |
Schistosoma mansoni | tyrosine kinase | 0.0138 | 0.1011 | 0.1163 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.0081 | 0.0153 | 0.0176 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0138 | 0.1011 | 0.1011 |
Onchocerca volvulus | 0.0081 | 0.0153 | 0.151 | |
Brugia malayi | Protein kinase domain containing protein | 0.0138 | 0.1011 | 0.2553 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0138 | 0.1011 | 0.1011 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0081 | 0.0153 | 0.0176 |
Echinococcus granulosus | NCK adaptor protein | 0.0081 | 0.0153 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0138 | 0.1011 | 0.2553 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0406 | 0.5023 | 0.5023 |
Echinococcus multilocularis | suppressor of cytokine signaling 7 | 0.0081 | 0.0153 | 0.0153 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0335 | 0.3959 | 0.4556 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0081 | 0.0153 | 0.0386 |
Onchocerca volvulus | 0.0138 | 0.1011 | 1 | |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0138 | 0.1011 | 0.1011 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Onchocerca volvulus | 0.0081 | 0.0153 | 0.151 | |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0138 | 0.1011 | 0.2553 |
Echinococcus granulosus | SH2 domain containing adapter protein F | 0.0081 | 0.0153 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Brugia malayi | Variant SH3 domain containing protein | 0.0081 | 0.0153 | 0.0386 |
Echinococcus granulosus | Ribosomal protein S1 RNA binding domain | 0.0138 | 0.1012 | 0.1012 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0138 | 0.1011 | 0.2553 |
Onchocerca volvulus | 0.0138 | 0.1011 | 1 | |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0138 | 0.1011 | 0.1011 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0081 | 0.0153 | 0.151 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0267 | 0.2947 | 0.2947 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0315 | 0.3666 | 0.3666 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0406 | 0.5023 | 0.5023 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0138 | 0.1011 | 0.1011 |
Brugia malayi | Protein kinase domain containing protein | 0.0138 | 0.1011 | 0.2553 |
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein (hisJ) | 0.0355 | 0.4258 | 0.5 |
Echinococcus multilocularis | signal transduction protein lnk realted | 0.0081 | 0.0153 | 0.0153 |
Schistosoma mansoni | tyrosine-protein kinase zap-70 | 0.0081 | 0.0153 | 0.0176 |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.0138 | 0.1011 | 0.1011 |
Echinococcus multilocularis | SHC transforming protein 3 | 0.0081 | 0.0153 | 0.0153 |
Loa Loa (eye worm) | STAT protein | 0.0081 | 0.0153 | 0.0386 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.0138 | 0.1011 | 0.1011 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Echinococcus multilocularis | NCK adaptor protein | 0.0081 | 0.0153 | 0.0153 |
Brugia malayi | Tensin | 0.0081 | 0.0153 | 0.0386 |
Brugia malayi | Variant SH3 domain containing protein | 0.0081 | 0.0153 | 0.0386 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0406 | 0.5023 | 0.5023 |
Echinococcus granulosus | SH2 domain containing protein 7 | 0.0081 | 0.0153 | 0.0153 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0406 | 0.5023 | 0.5023 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0128 | 0.0858 | 0.2167 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0138 | 0.1011 | 0.1011 |
Echinococcus multilocularis | SH2 motif | 0.0081 | 0.0153 | 0.0153 |
Brugia malayi | SH2 domain containing protein | 0.0081 | 0.0153 | 0.0386 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0138 | 0.1011 | 0.1011 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.0858 | 0.2167 |
Onchocerca volvulus | 0.0081 | 0.0153 | 0.151 | |
Echinococcus granulosus | expressed conserved protein | 0.0081 | 0.0153 | 0.0153 |
Echinococcus granulosus | glutamate receptor 2 | 0.0406 | 0.5023 | 0.5023 |
Brugia malayi | Protein kinase domain containing protein | 0.0138 | 0.1011 | 0.2553 |
Echinococcus granulosus | SH2 motif | 0.0081 | 0.0153 | 0.0153 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0335 | 0.3959 | 0.3959 |
Schistosoma mansoni | tensin | 0.0081 | 0.0153 | 0.0176 |
Onchocerca volvulus | 0.0128 | 0.0858 | 0.849 | |
Echinococcus granulosus | tyrosine kinase | 0.0138 | 0.1011 | 0.1011 |
Echinococcus granulosus | glutamate receptor ionotropic kainate 3 | 0.0138 | 0.1012 | 0.1012 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0138 | 0.1011 | 0.1011 |
Onchocerca volvulus | 0.0138 | 0.1011 | 1 | |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0406 | 0.5023 | 0.5023 |
Brugia malayi | Variant SH3 domain containing protein | 0.0081 | 0.0153 | 0.0386 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0335 | 0.3959 | 0.4556 |
Echinococcus multilocularis | Ribosomal protein S1, RNA binding domain | 0.0138 | 0.1012 | 0.1012 |
Loa Loa (eye worm) | RhoGAP domain-containing protein | 0.0081 | 0.0153 | 0.0386 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0138 | 0.1011 | 0.1011 |
Onchocerca volvulus | 0.0138 | 0.1011 | 1 | |
Brugia malayi | SH2 domain containing protein | 0.0081 | 0.0153 | 0.0386 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0138 | 0.1011 | 0.2553 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0138 | 0.1011 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.0153 | 0.0176 |
Schistosoma mansoni | tyrosine kinase | 0.0128 | 0.0858 | 0.0987 |
Loa Loa (eye worm) | cytokine inducible SH2-containing protein 5 | 0.0081 | 0.0153 | 0.0386 |
Echinococcus granulosus | suppressor of cytokine signaling 7 | 0.0081 | 0.0153 | 0.0153 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0081 | 0.0153 | 0.0153 |
Chlamydia trachomatis | glutamine binding protein | 0.0355 | 0.4258 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0081 | 0.0153 | 0.151 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Brugia malayi | tRNA modification GTPase TrmE family protein | 0.0081 | 0.0153 | 0.0386 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0244 | 0.2602 | 0.2602 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0138 | 0.1011 | 0.1011 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0191 | 0.1803 | 0.1803 |
Schistosoma mansoni | shc transforming protein | 0.0081 | 0.0153 | 0.0176 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0138 | 0.1011 | 0.2553 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.0138 | 0.1012 | 0.1012 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0138 | 0.1011 | 0.1011 |
Entamoeba histolytica | SH2 domain containing protein | 0.0081 | 0.0153 | 0.151 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0138 | 0.1011 | 0.1011 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0138 | 0.1011 | 0.1011 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0191 | 0.1803 | 0.4554 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0138 | 0.1011 | 0.1011 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0138 | 0.1011 | 0.1011 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0138 | 0.1011 | 0.1011 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.0081 | 0.0153 | 0.0386 |
Echinococcus granulosus | hypothetical protein | 0.0081 | 0.0153 | 0.0153 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0138 | 0.1011 | 0.1011 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0138 | 0.1011 | 0.1011 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0335 | 0.3959 | 1 |
Echinococcus multilocularis | tensin | 0.0081 | 0.0153 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Echinococcus granulosus | signal transduction protein lnk realted | 0.0081 | 0.0153 | 0.0153 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.0081 | 0.0153 | 0.0176 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0138 | 0.1011 | 0.1011 |
Brugia malayi | Protein kinase domain containing protein | 0.0138 | 0.1011 | 0.2553 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0191 | 0.1803 | 0.1803 |
Echinococcus multilocularis | suppressor of cytokine signaling 6 | 0.0081 | 0.0153 | 0.0153 |
Echinococcus granulosus | suppressor of cytokine signaling 6 | 0.0081 | 0.0153 | 0.0153 |
Echinococcus multilocularis | receptor type guanylyl cyclase | 0.0128 | 0.0858 | 0.0858 |
Schistosoma mansoni | tyrosine kinase | 0.0138 | 0.1011 | 0.1163 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0081 | 0.0153 | 0.0386 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0081 | 0.0153 | 0.0153 |
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein | 0.0355 | 0.4258 | 0.5 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0335 | 0.3959 | 1 |
Echinococcus granulosus | glutamate receptor ionotropic kainate | 0.0138 | 0.1012 | 0.1012 |
Schistosoma mansoni | tyrosine kinase | 0.0138 | 0.1011 | 0.1163 |
Loa Loa (eye worm) | TK protein kinase | 0.0138 | 0.1011 | 0.2553 |
Echinococcus multilocularis | guanine nucleotide exchange factor VAV2 | 0.0081 | 0.0153 | 0.0153 |
Brugia malayi | RhoGAP domain containing protein | 0.0081 | 0.0153 | 0.0386 |
Loa Loa (eye worm) | SRC-1 | 0.0138 | 0.1011 | 0.2553 |
Echinococcus granulosus | tensin C1 domain containing phosphatase | 0.0081 | 0.0153 | 0.0153 |
Echinococcus granulosus | SH2 motif | 0.0081 | 0.0153 | 0.0153 |
Trypanosoma cruzi | extracellular receptor, putative | 0.0071 | 0 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.0138 | 0.1011 | 0.1011 |
Onchocerca volvulus | Atrial natriuretic peptide receptor 3 homolog | 0.0128 | 0.0858 | 0.849 |
Onchocerca volvulus | 0.0111 | 0.0594 | 0.5877 | |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0081 | 0.0153 | 0.0153 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0081 | 0.0153 | 0.0386 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.0153 | 0.0176 |
Echinococcus multilocularis | tyrosine kinase | 0.0128 | 0.0858 | 0.0858 |
Onchocerca volvulus | 0.0138 | 0.1011 | 1 | |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0737 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0138 | 0.1011 | 0.1011 |
Echinococcus granulosus | phosphatidylinositol 3 kinase regulatory subunit | 0.0081 | 0.0153 | 0.0153 |
Schistosoma mansoni | glutamate receptor NMDA | 0.065 | 0.8689 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0153 | 0.0386 |
Onchocerca volvulus | 0.0081 | 0.0153 | 0.151 | |
Onchocerca volvulus | 0.0081 | 0.0153 | 0.151 | |
Brugia malayi | Glutamate receptor 2 precursor | 0.0335 | 0.3959 | 1 |
Schistosoma mansoni | adapter molecule crk | 0.0081 | 0.0153 | 0.0176 |
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.0138 | 0.1012 | 0.1012 |
Onchocerca volvulus | 0.0138 | 0.1011 | 1 | |
Echinococcus granulosus | N chimaerin | 0.0081 | 0.0153 | 0.0153 |
Echinococcus multilocularis | N chimaerin | 0.0081 | 0.0153 | 0.0153 |
Echinococcus granulosus | receptor type guanylyl cyclase | 0.0128 | 0.0858 | 0.0858 |
Echinococcus granulosus | tyrosine kinase | 0.0128 | 0.0858 | 0.0858 |
Mycobacterium tuberculosis | Probable glutamine-binding lipoprotein GlnH (GLNBP) | 0.0355 | 0.4258 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0138 | 0.1011 | 0.2553 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 0.38 mg kg-1 | Effective dose of the compound was determined against Candida albicans KB-8 strain after po administration in murine | ChEMBL. | No reference |
ED50 (functional) | = 0.38 mg kg-1 | Effective dose of the compound was determined against Candida albicans KB-8 strain after po administration in murine | ChEMBL. | No reference |
ED50 (functional) | = 18 mg kg-1 | Effective dose of the compound was determined against Aspergillus fumigatus MTU6001 strain after po administration in murine | ChEMBL. | No reference |
ED50 (functional) | = 18 mg kg-1 | Effective dose of the compound was determined against Aspergillus fumigatus MTU6001 strain after po administration in murine | ChEMBL. | No reference |
MIC (functional) | = 0.2 ug ml-1 | Minimum inhibitory concentration required for in vitro antifungal activity against Candida albicans KB-8 strain | ChEMBL. | No reference |
MIC (functional) | = 0.2 ug ml-1 | Minimum inhibitory concentration required for in vitro antifungal activity against Candida albicans KB-8 strain | ChEMBL. | No reference |
MIC (functional) | = 12.5 ug ml-1 | Minimum inhibitory concentration required for in vitro antifungal activity against Aspergillus fumigatus MTU6001 strain | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.