Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | > 32 ug ml-1 | In vitro minimum inhibitory concentration of compound against Mycobacterium smegmatis MTCC 006 | ChEMBL. | 15603950 |
MIC (functional) | > 32 ug ml-1 | In vitro minimum inhibitory concentration of compound against Methicillin-sensitive Staphylococcus aureus ATCC 29213 | ChEMBL. | 15603950 |
MIC (functional) | > 32 ug ml-1 | In vitro minimum inhibitory concentration of compound against Staphylococcus aureus ATCC 49951 (Smith) | ChEMBL. | 15603950 |
MIC (functional) | > 32 ug ml-1 | In vitro minimum inhibitory concentration of compound against Methicillin-resistant Staphylococcus aureus ATCC 29213 | ChEMBL. | 15603950 |
MIC (functional) | > 32 ug ml-1 | In vitro minimum inhibitory concentration against Enterococcus faecalis ATCC 29212 | ChEMBL. | 15603950 |
MIC (functional) | > 32 ug ml-1 | In vitro minimum inhibitory concentration against vancomycin-resistant Enterococcus faecalis NCTC 12201 | ChEMBL. | 15603950 |
MIC (functional) | > 32 ug ml-1 | In vitro minimum inhibitory concentration against vancomycin-resistant Enterococcus faecium NCTC 12202 | ChEMBL. | 15603950 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.