Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | adrenoceptor alpha 1A | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.1246 | 1 |
Brugia malayi | amidase | 0.0107 | 0.1246 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0107 | 0.1246 | 1 |
Schistosoma mansoni | amidase | 0.0107 | 0.1246 | 1 |
Giardia lamblia | Kinase, CMGC GSK | 0.0043 | 0 | 0.5 |
Onchocerca volvulus | 0.0058 | 0.0286 | 1 | |
Loa Loa (eye worm) | O-methyltransferase | 0.0058 | 0.0286 | 0.2296 |
Onchocerca volvulus | 0.0058 | 0.0286 | 1 | |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0107 | 0.1246 | 1 |
Brugia malayi | O-methyltransferase family protein | 0.0058 | 0.0286 | 0.2296 |
Wolbachia endosymbiont of Brugia malayi | O-methyltransferase | 0.0058 | 0.0286 | 0.5 |
Schistosoma mansoni | o-methyltransferase | 0.0058 | 0.0286 | 0.2296 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0107 | 0.1246 | 1 |
Plasmodium falciparum | glycogen synthase kinase 3 | 0.0043 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0043 | 0 | 0.5 |
Brugia malayi | O-methyltransferase family protein | 0.0058 | 0.0286 | 0.2296 |
Brugia malayi | O-methyltransferase family protein | 0.0058 | 0.0286 | 0.2296 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0107 | 0.1246 | 1 |
Trypanosoma cruzi | glycogen synthase kinase 3, putative | 0.0043 | 0 | 0.5 |
Plasmodium vivax | glycogen synthase kinase 3, putative | 0.0043 | 0 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0043 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable catechol-O-methyltransferase | 0.05 | 0.8875 | 1 |
Giardia lamblia | Kinase, CMGC GSK | 0.0043 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE METHYLTRANSFERASE | 0.0058 | 0.0286 | 0.5 |
Brugia malayi | O-methyltransferase | 0.0058 | 0.0286 | 0.2296 |
Schistosoma mansoni | o-methyltransferase | 0.0058 | 0.0286 | 0.2296 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0043 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0286 | 0.2296 |
Trypanosoma brucei | protein kinase, putative | 0.0043 | 0 | 0.5 |
Leishmania major | glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 | 0.0043 | 0 | 0.5 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0107 | 0.1246 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0043 | 0 | 0.5 |
Schistosoma mansoni | o-methyltransferase | 0.0058 | 0.0286 | 0.2296 |
Toxoplasma gondii | cell-cycle-associated protein kinase GSK, putative | 0.0043 | 0 | 0.5 |
Schistosoma mansoni | o-methyltransferase | 0.0058 | 0.0286 | 0.2296 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0043 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.