Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | prostaglandin E synthase 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0021 | 0.0052 |
Brugia malayi | Uncoordinated protein 44 | 0.0062 | 0.00000014065 | 0.00000035585 |
Trypanosoma cruzi | glutathione-S-transferase/glutaredoxin, putative | 0.0163 | 0.3953 | 0.5 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0062 | 0.00000014065 | 0.00000014065 |
Brugia malayi | Death domain containing protein | 0.0062 | 0.00000014065 | 0.00000035585 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0062 | 0.00000014065 | 0.0001 |
Leishmania major | glutathione-S-transferase/glutaredoxin, putative | 0.0163 | 0.3953 | 0.5 |
Trypanosoma brucei | Prostaglandin E synthase | 0.0163 | 0.3953 | 0.5 |
Brugia malayi | hypothetical protein | 0.0163 | 0.3953 | 1 |
Onchocerca volvulus | 0.0163 | 0.3953 | 1 | |
Echinococcus multilocularis | Ankyrin | 0.0062 | 0.0021 | 0.0021 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0317 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.3953 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0062 | 0.00000014065 | 0.00000035585 |
Toxoplasma gondii | prostaglandin-E synthase | 0.0163 | 0.3953 | 0.5 |
Trypanosoma cruzi | glutathione-S-transferase/glutaredoxin, putative | 0.0163 | 0.3953 | 0.5 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0062 | 0.00000014065 | 0.00000014065 |
Echinococcus granulosus | Ankyrin | 0.0062 | 0.0021 | 0.0021 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0062 | 0.0021 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.