Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | prostaglandin E synthase 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0138 | 0.7701 | 0.5 |
Onchocerca volvulus | 0.0163 | 1 | 1 | |
Trypanosoma cruzi | glutathione-S-transferase/glutaredoxin, putative | 0.0163 | 1 | 1 |
Leishmania major | glutathione-S-transferase/glutaredoxin, putative | 0.0163 | 1 | 1 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0055 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 1 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0138 | 0.7701 | 0.5 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.0138 | 0.7701 | 0.7701 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0138 | 0.7701 | 0.7701 |
Echinococcus granulosus | prolyl endopeptidase | 0.0138 | 0.7701 | 0.5 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.0123 | 0.636 | 1 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0138 | 0.7701 | 0.5 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0055 | 0 | 0.5 |
Trypanosoma brucei | Prostaglandin E synthase | 0.0163 | 1 | 1 |
Trypanosoma cruzi | glutathione-S-transferase/glutaredoxin, putative | 0.0163 | 1 | 1 |
Trypanosoma brucei | prolyl endopeptidase | 0.0138 | 0.7701 | 0.7701 |
Toxoplasma gondii | prostaglandin-E synthase | 0.0163 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.