Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Bos taurus | Protein farnesyltransferase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.0067 | 0.078 | 0.5 |
Trichomonas vaginalis | geranylgeranyl transferase type I beta subunit, putative | 0.0067 | 0.078 | 0.5 |
Giardia lamblia | Prenyltransferase | 0.0067 | 0.078 | 0.5 |
Mycobacterium tuberculosis | Halimadienyl diphosphate synthase | 0.0074 | 0.1216 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0206 | 1 | 1 |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.0067 | 0.078 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0206 | 1 | 1 |
Trypanosoma brucei | lanosterol synthase | 0.0074 | 0.1216 | 1 |
Toxoplasma gondii | kringle domain-containing protein | 0.0206 | 1 | 1 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0206 | 1 | 1 |
Trichomonas vaginalis | type I geranylgeranyltransferase beta subunit, putative | 0.0067 | 0.078 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0206 | 1 | 1 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0206 | 1 | 1 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0206 | 1 | 1 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0206 | 1 | 1 |
Trichomonas vaginalis | geranylgeranyl transferase type beta subunit, putative | 0.0067 | 0.078 | 0.5 |
Onchocerca volvulus | 0.0206 | 1 | 0.5 | |
Entamoeba histolytica | protein farnesyltransferase beta subunit, putative | 0.0067 | 0.078 | 0.5 |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.0067 | 0.078 | 0.5 |
Brugia malayi | Kringle domain containing protein | 0.0206 | 1 | 1 |
Leishmania major | farnesyltransferase beta subunit | 0.0067 | 0.078 | 0.078 |
Leishmania major | hypothetical protein, conserved | 0.0206 | 1 | 1 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.0074 | 0.1216 | 0.0472 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.0074 | 0.1216 | 0.0472 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0206 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.