Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.25 ug ml-1 | Minimum inhibitory concentration of the compound against Staphylococcus pneumoniae OC4421 | ChEMBL. | 15357979 |
MIC (functional) | = 1 ug ml-1 | Minimum inhibitory concentration of the compound against Staphylococcus pneumoniae OC9132 | ChEMBL. | 15357979 |
MIC (functional) | = 4 ug ml-1 | Minimum inhibitory concentration of the compound against Staphylococcus aureus OC4172 | ChEMBL. | 15357979 |
MIC (functional) | = 8 ug ml-1 | Minimum inhibitory concentration of the compound against Staphylococcus aureus OC4172 in presence of mouse serum | ChEMBL. | 15357979 |
MIC (functional) | = 8 ug ml-1 | Minimum inhibitory concentration of the compound against Staphylococcus pneumoniae OC4051 | ChEMBL. | 15357979 |
MIC (functional) | > 16 ug ml-1 | Minimum inhibitory concentration of the compound against Staphylococcus haemolyticus OC3882 | ChEMBL. | 15357979 |
MIC (functional) | > 16 ug ml-1 | Minimum inhibitory concentration of the compound against Staphylococcus haemolyticus OC4545 | ChEMBL. | 15357979 |
MIC (functional) | = 16 ug ml-1 | Minimum inhibitory concentration of the compound against Haemophilus influenzae OC4482 | ChEMBL. | 15357979 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.