Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0135 | 0.0732 | 0.0732 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0164 | 0.1233 | 0.1185 |
Schistosoma mansoni | tyrosine kinase | 0.0162 | 0.1203 | 0.1155 |
Schistosoma mansoni | tyrosine kinase | 0.0162 | 0.1203 | 0.1155 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0097 | 0.0054 | 0.0054 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0657 | 1 | 1 |
Schistosoma mansoni | P2X receptor subunit | 0.0135 | 0.0732 | 0.0681 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.0657 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0164 | 0.1233 | 0.1185 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0135 | 0.0732 | 0.0732 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.0657 | 1 | 1 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0135 | 0.0732 | 0.0681 |
Schistosoma mansoni | P2X receptor subunit | 0.0135 | 0.0732 | 0.0681 |
Schistosoma mansoni | tyrosine kinase | 0.0305 | 0.3739 | 0.3704 |
Schistosoma mansoni | tyrosine kinase | 0.0164 | 0.1233 | 0.1185 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0305 | 0.3739 | 0.3704 |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.0657 | 1 | 1 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.0657 | 1 | 1 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0135 | 0.0732 | 0.0732 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0164 | 0.1233 | 0.1185 |
Leishmania major | 0.0657 | 1 | 0.5 | |
Schistosoma mansoni | P2X receptor subunit | 0.0135 | 0.0732 | 0.0681 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0305 | 0.3739 | 0.3704 |
Schistosoma mansoni | P2X receptor subunit | 0.0135 | 0.0732 | 0.0681 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0657 | 1 | 1 |
Echinococcus multilocularis | insulin receptor | 0.0097 | 0.0054 | 0.0054 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.0657 | 1 | 1 |
Toxoplasma gondii | fructose-bisphospatase II | 0.0657 | 1 | 1 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0135 | 0.0732 | 0.0681 |
Schistosoma mansoni | tyrosine kinase | 0.0162 | 0.1203 | 0.1155 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0164 | 0.1233 | 0.1233 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0305 | 0.3739 | 0.3739 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0135 | 0.0732 | 0.0681 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0305 | 0.3739 | 0.3704 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.