Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | < 0.22 uM | Concentration required to inhibit growth of african green monkey kidney cell line | ChEMBL. | 15317455 |
IC50 (functional) | = 2.16 uM | Concentration required to inhibit growth of human epidermoid carcinoma (KB) cell line | ChEMBL. | 15317455 |
IC50 (functional) | = 2.16 uM | Concentration required to inhibit growth of human epidermoid carcinoma (KB) cell line | ChEMBL. | 15317455 |
IC50 (functional) | = 2.83 uM | Concentration required to inhibit growth of human cervical carcinoma (HeLa) cell line | ChEMBL. | 15317455 |
IC50 (functional) | = 2.83 uM | Concentration required to inhibit growth of human cervical carcinoma (HeLa) cell line | ChEMBL. | 15317455 |
IC50 (functional) | = 3.14 uM | Concentration required to inhibit growth of human hepatocellular carcinoma (HepG2) cell line | ChEMBL. | 15317455 |
IC50 (functional) | = 3.14 uM | Concentration required to inhibit growth of human hepatocellular carcinoma (HepG2) cell line | ChEMBL. | 15317455 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 15317455 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.