TDR Targets

Basic information

Technical information

TDR Targets ID: 334188
Name: 2-[[3-[2-(1,1-diphenylpropylsulfanyl)ethyl]-2 -(hydroxymethyl)-1-benzofuran-7-yl]oxy]acetic acid
MW: 476.584 | Formula: C28H28O5S
H donors: 2 H acceptors: 3 LogP: 5.86 Rotable bonds: 11
Rule of 5 violations (Lipinski): 1
SMILES: OCc1oc2c(c1CCSC(c1ccccc1)(c1ccccc1)CC)cccc2OCC(=O)O
InChi: 1S/C28H28O5S/c1-2-28(20-10-5-3-6-11-20,21-12-7-4-8-13-21)34-17-16-22-23-14-9-15-24(32-19-26(30)31)27(23)33-25(22)18-29/h3-15,29H,2,16-19H2,1H3,(H,30,31)
InChiKey: ANAJKRIABHPZSH-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

2-[3-[2-(1,1-diphenylpropylsulfanyl)ethyl]-2-(hydroxymethyl)benzofuran-7-yl]oxyacetic acid
2-[[3-[2-(1,1-diphenylpropylthio)ethyl]-2-(hydroxymethyl)-7-benzofuranyl]oxy]acetic acid
2-[[3-[2-(1,1-diphenylpropylsulfanyl)ethyl]-2-(hydroxymethyl)-1-benzofuran-7-yl]oxy]ethanoic acid
2-[3-[2-(1,1-diphenylpropylthio)ethyl]-2-methylol-benzofuran-7-yl]oxyacetic acid
2-[[3-[2-[1,1-di(phenyl)propylsulfanyl]ethyl]-2-(hydroxymethyl)-1-benzofuran-7-yl]oxy]acetic acid
2-[3-[2-[1,1-di(phenyl)propylsulfanyl]ethyl]-2-(hydroxymethyl)benzofuran-7-yl]oxyacetic acid
2-[[3-[2-[1,1-di(phenyl)propylthio]ethyl]-2-(hydroxymethyl)-7-benzofuranyl]oxy]acetic acid
2-[3-[2-[1,1-di(phenyl)propylthio]ethyl]-2-methylol-benzofuran-7-yl]oxyacetic acid
2-[[3-[2-[1,1-di(phenyl)propylsulfanyl]ethyl]-2-(hydroxymethyl)-1-benzofuran-7-yl]oxy]ethanoic acid

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	thromboxane A2 receptor	Starlite/ChEMBL	References
Homo sapiens	prostaglandin I2 (prostacyclin) receptor (IP)	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Loa Loa (eye worm)	acetylcholine receptor protein	0.0054	0.1442	0.3605
Echinococcus granulosus	Cys loop ligand gated ion channel subunit	0.0054	0.1442	0.1442
Trypanosoma brucei	Phosphatidylinositol 3-kinase tor1	0.0019	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.1442	0.3605
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.1442	0.3605
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Schistosoma mansoni	nAChR subunit	0.0118	0.4001	1
Echinococcus granulosus	nAChR subunit	0.0118	0.4001	0.4001
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Echinococcus multilocularis	nicotinic acetylcholine receptor a11 subunit	0.0118	0.4001	0.4001
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0118	0.4001	0.4001
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Echinococcus granulosus	Cys loop ligand gated ion channel subunit	0.0118	0.4001	0.4001
Echinococcus granulosus	nicotinic acetylcholine receptor alpha subunit	0.0118	0.4001	0.4001
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Brugia malayi	acetylcholine receptor alpha subunit precursor, putative	0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0063	0.181	0.4524
Brugia malayi	acetylcholine receptor protein, alpha-like chain, putative	0.0118	0.4001	1
Trypanosoma cruzi	hypothetical protein, conserved	0.0093	0.3011	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Schistosoma mansoni	neurotransmitter gated ion channel	0.0063	0.181	0.4524
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Echinococcus granulosus	nAChR subunit	0.0063	0.181	0.181
Loa Loa (eye worm)	hypothetical protein	0.0054	0.1442	0.3605
Brugia malayi	hypothetical protein	0.0054	0.1442	0.3605
Loa Loa (eye worm)	nicotinic acetylcholine receptor non-alpha subunit	0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Loa Loa (eye worm)	excitatory GABA receptor EXP-1A	0.0118	0.4001	1
Schistosoma mansoni	nAChR subunit (ShAR1-beta2-like)	0.0118	0.4001	1
Schistosoma mansoni	nAChR subunit	0.0118	0.4001	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Schistosoma mansoni	nicotinic acetylcholine receptor alpha	0.0063	0.181	0.4524
Trypanosoma brucei	phosphatidylinositol 3-kinase, putative	0.0019	0	0.5
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0118	0.4001	1
Brugia malayi	excitatory GABA receptor EXP-1A	0.0118	0.4001	1
Echinococcus granulosus	acetylcholine receptor subunit beta 1	0.0118	0.4001	0.4001
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Echinococcus multilocularis	neuronal acetylcholine receptor subunit alpha 4	0.0118	0.4001	0.4001
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0118	0.4001	1
Echinococcus granulosus	nicotinic acetylcholine receptor beta 1 subunit	0.0118	0.4001	0.4001
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Schistosoma mansoni	nAChR subunit	0.0054	0.1442	0.3605
Schistosoma mansoni	nAChR subunit	0.0118	0.4001	1
Echinococcus granulosus	glycine receptor subunit beta	0.0118	0.4001	0.4001
Loa Loa (eye worm)	hypothetical protein	0.0063	0.181	0.4524
Echinococcus multilocularis	nicotinic acetylcholine receptor subunit type	0.0054	0.1442	0.1442
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0118	0.4001	1
Brugia malayi	glutamate-gated chloride channel alpha3A subunit, putative	0.0063	0.181	0.4524
Loa Loa (eye worm)	hypothetical protein	0.0063	0.181	0.4524
Loa Loa (eye worm)	hypothetical protein	0.0054	0.1442	0.3605
Onchocerca volvulus		0.0118	0.4001	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Loa Loa (eye worm)	ligand-Gated ion Channel family member	0.0118	0.4001	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Onchocerca volvulus		0.0063	0.181	0.1438
Echinococcus granulosus	nicotinic acetylcholine receptor subunit type	0.0118	0.4001	0.4001
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Onchocerca volvulus	Putative nachr subunit	0.0118	0.4001	1
Brugia malayi	Cation transporter family protein	0.0118	0.4001	1
Toxoplasma gondii	target of rapamycin (TOR), putative	0.0019	0	0.5
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Brugia malayi	nicotinic acetylcholine receptor beta-1 chain precursor	0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0118	0.4001	1
Loa Loa (eye worm)	glutamate-gated chloride channel alpha3A subunit	0.0054	0.1442	0.3605
Loa Loa (eye worm)	hypothetical protein	0.0054	0.1442	0.3605
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.1442	0.3605
Echinococcus multilocularis	nicotinic acetylcholine receptor beta 1 subunit	0.0118	0.4001	0.4001
Trypanosoma brucei	phosphatidylinositol 4-kinase, putative	0.0019	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0063	0.181	0.4524
Loa Loa (eye worm)	hypothetical protein	0.0054	0.1442	0.3605
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0118	0.4001	1
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0118	0.4001	1
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0118	0.4001	0.4001
Trypanosoma brucei	phosphatidylinositol 3-related kinase, putative	0.0019	0	0.5
Loa Loa (eye worm)	GABA receptor subunit	0.0063	0.181	0.4524
Loa Loa (eye worm)	ACC-1 protein	0.0118	0.4001	1
Onchocerca volvulus		0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.1442	0.3605
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0118	0.4001	0.4001
Brugia malayi	Hypothetical glycine receptor like protein T20B12.9 in chromosome III	0.0118	0.4001	1
Brugia malayi	Hypothetical glycine receptor like protein T20B12.9 in chromosome III	0.0063	0.181	0.4524
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Brugia malayi	hypothetical protein	0.0054	0.1442	0.3605
Leishmania major	hypothetical protein, conserved	0.0097	0.3155	1
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Echinococcus multilocularis	nAChR subunit	0.0063	0.181	0.181
Schistosoma mansoni	neurotransmitter gated ion channel	0.0054	0.1442	0.3605
Brugia malayi	Cation transporter family protein	0.0118	0.4001	1
Echinococcus multilocularis	nicotinic acetylcholine receptor alpha subunit	0.0118	0.4001	0.4001
Loa Loa (eye worm)	LGC-31 protein	0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.1442	0.3605
Loa Loa (eye worm)	nicotinic acetylcholine receptor alpha subunit	0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.1442	0.3605
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Echinococcus multilocularis	acetylcholine receptor subunit beta 1	0.0118	0.4001	0.4001
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0054	0.1442	0.3605
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0118	0.4001	0.4001
Schistosoma mansoni	neurotransmitter gated ion channel	0.0054	0.1442	0.3605
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0063	0.181	0.4524
Entamoeba histolytica	hypothetical protein	0.0063	0.181	1
Giardia lamblia	GTOR	0.0019	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0054	0.1442	0.3605
Loa Loa (eye worm)	acetylcholine receptor alpha subunit	0.0118	0.4001	1
Brugia malayi	Neuronal acetylcholine receptor protein, alpha-2 chain precursor	0.0054	0.1442	0.3605
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Brugia malayi	hypothetical protein	0.0054	0.1442	0.3605
Echinococcus granulosus	gamma aminobutyric acid receptor subunit	0.0054	0.1442	0.1442
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Brugia malayi	acetylcholine receptor, alpha-type subunit unc-38 precursor	0.0118	0.4001	1
Echinococcus granulosus	glycine receptor subunit beta	0.0118	0.4001	0.4001
Schistosoma mansoni	nAChR subunit	0.0118	0.4001	1
Onchocerca volvulus		0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.1442	0.3605
Brugia malayi	hypothetical protein	0.0054	0.1442	0.3605
Trypanosoma brucei	target of rapamycin kinase 3, putative	0.0019	0	0.5
Schistosoma mansoni	nAChR subunit	0.0118	0.4001	1
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0118	0.4001	1
Schistosoma mansoni	acetylcholine receptor-related	0.0054	0.1442	0.3605
Echinococcus multilocularis	nicotinic acetylcholine receptor subunit alpha 8	0.0118	0.4001	0.4001
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0118	0.4001	0.4001
Loa Loa (eye worm)	hypothetical protein	0.0063	0.181	0.4524
Brugia malayi	Acetylcholine receptor protein, alpha-like chain 1 precursor	0.0054	0.1442	0.3605
Loa Loa (eye worm)	ACC-1 protein	0.0118	0.4001	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0054	0.1442	0.3605
Schistosoma mansoni	nAChR subunit	0.0118	0.4001	1
Onchocerca volvulus		0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0063	0.181	0.4524
Loa Loa (eye worm)	neuronal acetylcholine receptor protein	0.0054	0.1442	0.3605
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0063	0.181	0.4524
Echinococcus granulosus	nicotinic acetylcholine receptor subunit alpha 8	0.0118	0.4001	0.4001
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Echinococcus multilocularis	Cys loop ligand gated ion channel subunit	0.0118	0.4001	0.4001
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0063	0.181	0.4524
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0118	0.4001	1
Brugia malayi	glutamate-gated chloride channel alpha3A subunit, putative	0.0054	0.1442	0.3605
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0118	0.4001	0.4001
Echinococcus multilocularis	nAChR subunit	0.0118	0.4001	0.4001
Schistosoma mansoni	nAChR subunit (ShAR1-beta-like)	0.0118	0.4001	1
Schistosoma mansoni	nAChR subunit	0.0054	0.1442	0.3605
Schistosoma mansoni	nAChR subunit (ShAR1-alpha-like)	0.0118	0.4001	1
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0054	0.1442	0.3605
Echinococcus granulosus	nicotinic acetylcholine receptor a11 subunit	0.0118	0.4001	0.4001
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0063	0.181	0.4524
Echinococcus multilocularis	Cys loop ligand gated ion channel subunit	0.0054	0.1442	0.1442
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Echinococcus multilocularis	glycine receptor subunit beta	0.0118	0.4001	0.4001
Onchocerca volvulus		0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0063	0.181	0.4524
Onchocerca volvulus		0.0063	0.181	0.1438
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Echinococcus multilocularis	glycine receptor subunit beta	0.0118	0.4001	0.4001
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0118	0.4001	1
Brugia malayi	hypothetical protein	0.0054	0.1442	0.3605
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Echinococcus multilocularis	gamma aminobutyric acid receptor subunit	0.0054	0.1442	0.1442
Loa Loa (eye worm)	hypothetical protein	0.0063	0.181	0.4524
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0054	0.1442	0.3605
Echinococcus multilocularis	DNA dependent protein kinase catalytic subunit	0.0266	1	1
Brugia malayi	gamma-aminobutyric-acid receptor beta subunit precursor	0.0118	0.4001	1
Loa Loa (eye worm)	glutamate-gated chloride channel alpha3A subunit	0.0118	0.4001	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0054	0.1442	0.3605
Schistosoma mansoni	acetylcholine receptor subunit beta	0.0054	0.1442	0.3605
Schistosoma mansoni	nAChR subunit	0.0118	0.4001	1
Onchocerca volvulus		0.0118	0.4001	1
Brugia malayi	nicotinic acetylcholine receptor alpha subunit, putative	0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Echinococcus granulosus	neuronal acetylcholine receptor subunit alpha 4	0.0118	0.4001	0.4001
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0118	0.4001	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.1442	0.3605
Loa Loa (eye worm)	hypothetical protein	0.0118	0.4001	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0	0.5
Brugia malayi	Cation transporter family protein	0.0118	0.4001	1

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (functional)	= 3.8 uM	Inhibition of U-46,619 (2 uM) induced platelet aggregation in human platelet rich plasma	ChEMBL.	16078846
IC50 (functional)	= 3.8 uM	Inhibition of U-46,619 (2 uM) induced platelet aggregation in human platelet rich plasma	ChEMBL.	16078846
IC50 (functional)	= 56 uM	Inhibition of ADP (5 uM) induced platelet aggregation in human platelet rich plasma	ChEMBL.	16078846
IC50 (functional)	= 56 uM	Inhibition of ADP (5 uM) induced platelet aggregation in human platelet rich plasma	ChEMBL.	16078846
Ki (binding)	= 0.18 uM	Inhibition of [3H]-SQ-29,548 binding to thromboxane A2 receptors (TP) of human platelet membrane	ChEMBL.	16078846
Ki (binding)	= 0.18 uM	Inhibition of [3H]-SQ-29,548 binding to thromboxane A2 receptors (TP) of human platelet membrane	ChEMBL.	16078846
Ki (binding)	= 3.4 uM	Inhibition of [3H]-APS-314d binding to prostacyclin receptors (IP) of human platelet membrane	ChEMBL.	16078846
Ki (binding)	= 3.4 uM	Inhibition of [3H]-APS-314d binding to prostacyclin receptors (IP) of human platelet membrane	ChEMBL.	16078846

Phenotypes

Whole-cell/tissue/organism interactions

Species name	Source	Reference	Is orphan
Homo sapiens	ChEMBL23	16078846

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL189694
PubChem: 11260506

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 334188