Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0439 | 0.083 | 0.1326 |
Echinococcus multilocularis | integrin alpha 3 | 0.1567 | 0.4643 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1128 | 0.3158 | 0.283 |
Brugia malayi | Integrin alpha cytoplasmic region family protein | 0.1546 | 0.4573 | 0.7097 |
Echinococcus granulosus | integrin alpha ps | 0.0439 | 0.083 | 0.1477 |
Loa Loa (eye worm) | hypothetical protein | 0.0477 | 0.0958 | 0.0524 |
Echinococcus multilocularis | integrin alpha ps | 0.0916 | 0.2443 | 0.5083 |
Echinococcus granulosus | integrin alpha ps | 0.0916 | 0.2443 | 0.5083 |
Schistosoma mansoni | integrin alpha-ps | 0.0477 | 0.0958 | 0.1531 |
Loa Loa (eye worm) | hypothetical protein | 0.0439 | 0.083 | 0.039 |
Echinococcus multilocularis | integrin alpha ps | 0.0439 | 0.083 | 0.1477 |
Echinococcus granulosus | integrin alpha 3 | 0.1567 | 0.4643 | 1 |
Echinococcus multilocularis | integrin alpha ps | 0.0916 | 0.2443 | 0.5083 |
Schistosoma mansoni | integrin alpha-ps | 0.0916 | 0.2443 | 0.3905 |
Loa Loa (eye worm) | hypothetical protein | 0.1546 | 0.4573 | 0.4313 |
Schistosoma mansoni | integrin alpha | 0.2044 | 0.6257 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1605 | 0.4771 | 0.4521 |
Brugia malayi | Integrin alpha pat-2 precursor | 0.2044 | 0.6257 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.