Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 0.0912 | 0.1033 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | amine GPCR | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0121 | 0.0445 | 0.0504 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0568 | 0.2685 | 0.3042 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | neuropeptide receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0182 | 0.075 | 0.085 |
Brugia malayi | larval opioid receptor | 0.0182 | 0.075 | 0.075 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0182 | 0.075 | 0.085 |
Brugia malayi | neuropeptide F receptor | 0.0182 | 0.075 | 0.075 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0182 | 0.075 | 0.075 |
Brugia malayi | G protein-coupled receptor | 0.0182 | 0.075 | 0.075 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | opsin-like receptor | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | biogenic amine receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0419 | 0.1938 | 0.2196 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | orexin receptor type 2 | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | g protein coupled receptor | 0.0182 | 0.075 | 0.085 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0182 | 0.075 | 0.5 |
Echinococcus multilocularis | somatostatin receptor | 0.0182 | 0.075 | 0.085 |
Brugia malayi | AKH receptor | 0.0182 | 0.075 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0103 | 0.0358 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0182 | 0.075 | 0.085 |
Brugia malayi | Dopamine receptor protein 1 | 0.0182 | 0.075 | 0.075 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0103 | 0.0358 | 0.5 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0182 | 0.075 | 0.085 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0182 | 0.075 | 0.075 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0182 | 0.075 | 0.085 |
Brugia malayi | hypothetical protein | 0.0182 | 0.075 | 0.075 |
Schistosoma mansoni | opsin-like receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | sex peptide receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | amine GPCR | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | amine GPCR | 0.0182 | 0.075 | 0.085 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Echinococcus multilocularis | serotonin receptor | 0.1794 | 0.8826 | 1 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0182 | 0.075 | 0.085 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0182 | 0.075 | 0.075 |
Brugia malayi | sulfakinin receptor protein | 0.0182 | 0.075 | 0.075 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative | 0.0241 | 0.1046 | 0.1046 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0182 | 0.075 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | fmrfamide receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | g protein coupled receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | g-protein coupled receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | somatostatin receptor | 0.0182 | 0.075 | 0.085 |
Brugia malayi | Dopamine receptor protein 2 | 0.0182 | 0.075 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Brugia malayi | hypothetical protein | 0.0182 | 0.075 | 0.075 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0182 | 0.075 | 0.075 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0111 | 0.0394 | 0.0447 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0182 | 0.075 | 0.085 |
Brugia malayi | hypothetical protein | 0.0182 | 0.075 | 0.075 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0182 | 0.075 | 0.085 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0182 | 0.075 | 0.075 |
Schistosoma mansoni | biogenic amine receptor | 0.0182 | 0.075 | 0.085 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0182 | 0.075 | 0.075 |
Schistosoma mansoni | neuropeptide receptor | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | histamine h1 receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | neuropeptide receptor | 0.0182 | 0.075 | 0.085 |
Brugia malayi | G-protein coupled receptor | 0.0182 | 0.075 | 0.075 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0182 | 0.075 | 0.085 |
Brugia malayi | hypothetical protein | 0.0078 | 0.0229 | 0.0229 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0182 | 0.075 | 0.085 |
Brugia malayi | hypothetical protein | 0.0182 | 0.075 | 0.075 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0182 | 0.075 | 0.085 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0419 | 0.1938 | 1 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | allatostatin A receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0182 | 0.075 | 0.085 |
Brugia malayi | hypothetical protein | 0.0182 | 0.075 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0111 | 0.0394 | 0.0447 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0182 | 0.075 | 0.5 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0241 | 0.1046 | 0.1185 |
Schistosoma mansoni | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.1794 | 0.8826 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1794 | 0.8826 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0182 | 0.075 | 0.085 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0419 | 0.1938 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0182 | 0.075 | 0.085 |
Brugia malayi | Serotonin receptor | 0.0182 | 0.075 | 0.075 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0182 | 0.075 | 0.085 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Schistosoma mansoni | biogenic amine receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0182 | 0.075 | 0.085 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0182 | 0.075 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0121 | 0.0445 | 0.0504 |
Brugia malayi | Acyl-CoA oxidase family protein | 0.0649 | 0.3089 | 0.3089 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0419 | 0.1938 | 1 |
Echinococcus multilocularis | sex peptide receptor | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase | 0.0241 | 0.1046 | 0.1185 |
Echinococcus multilocularis | neuropeptide receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0182 | 0.075 | 0.085 |
Brugia malayi | Melatonin receptor type 1A | 0.0182 | 0.075 | 0.075 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0182 | 0.075 | 0.085 |
Mycobacterium ulcerans | acyl-CoA dehydrogenase | 0.0081 | 0.0243 | 0.5 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | neuropeptide s receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | neuropeptide receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0182 | 0.075 | 0.085 |
Brugia malayi | hypothetical protein | 0.0182 | 0.075 | 0.075 |
Loa Loa (eye worm) | acyl-CoA oxidase | 0.04 | 0.1844 | 0.2089 |
Brugia malayi | hypothetical protein | 0.0182 | 0.075 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.1794 | 0.8826 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0653 | 0.311 | 0.3524 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0241 | 0.1046 | 0.1185 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0182 | 0.075 | 0.085 |
Brugia malayi | G-protein coupled receptor | 0.0182 | 0.075 | 0.075 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0182 | 0.075 | 0.085 |
Toxoplasma gondii | acyl-CoA dehydrogenase, middle domain-containing protein | 0.0649 | 0.3089 | 0.5 |
Brugia malayi | follicle stimulating hormone receptor | 0.0182 | 0.075 | 0.075 |
Echinococcus granulosus | neuropeptide receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0653 | 0.311 | 0.3524 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0229 | 0.0259 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | amine GPCR | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | g protein coupled receptor | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0182 | 0.075 | 0.085 |
Brugia malayi | GnHR receptor homolog | 0.0182 | 0.075 | 0.075 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | fmrfamide receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0182 | 0.075 | 0.085 |
Brugia malayi | putative neuropeptide receptor | 0.0182 | 0.075 | 0.075 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0182 | 0.075 | 0.085 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0419 | 0.1938 | 0.1938 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0182 | 0.075 | 0.085 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0182 | 0.075 | 0.085 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Echinococcus granulosus | neuropeptide Y receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Brugia malayi | RE15519p | 0.0182 | 0.075 | 0.075 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0111 | 0.0394 | 0.0447 |
Echinococcus granulosus | serotonin receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | adenoreceptor | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | g protein coupled receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Brugia malayi | ORL1-like opioid receptor | 0.0182 | 0.075 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Brugia malayi | Dopamine receptor | 0.0182 | 0.075 | 0.075 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0182 | 0.075 | 0.075 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0111 | 0.0394 | 0.0394 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0182 | 0.075 | 0.075 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | PDE1B protein | 0.0241 | 0.1046 | 0.1185 |
Echinococcus multilocularis | g protein coupled receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Brugia malayi | neuropeptide F receptor | 0.0182 | 0.075 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Onchocerca volvulus | 0.0182 | 0.075 | 0.5 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | serotonin receptor | 0.1794 | 0.8826 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | fmrfamide receptor | 0.0182 | 0.075 | 0.085 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.1794 | 0.8826 | 1 |
Echinococcus granulosus | allatostatin A receptor | 0.0182 | 0.075 | 0.085 |
Brugia malayi | hypothetical protein | 0.0182 | 0.075 | 0.075 |
Schistosoma mansoni | myosin xvIII | 0.0182 | 0.075 | 0.085 |
Mycobacterium leprae | conserved hypothetical protein | 0.0078 | 0.0229 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | neuropeptide receptor | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | neuropeptide receptor | 0.0182 | 0.075 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0321 | 0.0364 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0182 | 0.075 | 0.085 |
Schistosoma mansoni | amine GPCR | 0.0182 | 0.075 | 0.085 |
Echinococcus multilocularis | g protein coupled receptor | 0.0182 | 0.075 | 0.085 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Drug uptake (functional) | = 0.02 nmol/mg | Intracellular level of putrescine in L1210 cells in the presence of DFMO at 25 uM | ChEMBL. | 16392808 |
Drug uptake (functional) | = 0.02 nmol/mg | Intracellular level of putrescine in L1210 cells in the presence of DFMO at 25 uM | ChEMBL. | 16392808 |
Drug uptake (functional) | = 1 nmol/mg | Intracellular level of putrescine in L1210 cells in the absence of DFMO at 25 uM | ChEMBL. | 16392808 |
Drug uptake (functional) | = 1 nmol/mg | Intracellular level of putrescine in L1210 cells in the absence of DFMO at 25 uM | ChEMBL. | 16392808 |
Drug uptake (ADMET) | = 1.2 nmol/mg | Cellular uptake in CHO-MG cells at 50 uM | ChEMBL. | 16392808 |
Drug uptake (functional) | = 1.2 nmol/mg | Intracellular level of conjugate in L1210 cells in the absence of DFMO at 25 uM | ChEMBL. | 16392808 |
Drug uptake (functional) | = 1.2 nmol/mg | Intracellular level of conjugate in L1210 cells in the absence of DFMO at 25 uM | ChEMBL. | 16392808 |
Drug uptake (ADMET) | = 1.3 nmol/mg | Cellular uptake in CHO cells at 50 uM | ChEMBL. | 16392808 |
Drug uptake (functional) | = 1.3 nmol/mg | Intracellular level of conjugate in L1210 cells in the presence of DFMO at 25 uM | ChEMBL. | 16392808 |
Drug uptake (functional) | = 1.3 nmol/mg | Intracellular level of conjugate in L1210 cells in the presence of DFMO at 25 uM | ChEMBL. | 16392808 |
Drug uptake (functional) | = 1.5 nmol/mg | Intracellular level of spermidine in L1210 cells in the presence of DFMO at 25 uM | ChEMBL. | 16392808 |
Drug uptake (functional) | = 1.5 nmol/mg | Intracellular level of spermidine in L1210 cells in the presence of DFMO at 25 uM | ChEMBL. | 16392808 |
Drug uptake (functional) | = 8.9 nmol/mg | Intracellular level of spermine in L1210 cells in the presence of DFMO at 25 uM | ChEMBL. | 16392808 |
Drug uptake (functional) | = 8.9 nmol/mg | Intracellular level of spermine in L1210 cells in the presence of DFMO at 25 uM | ChEMBL. | 16392808 |
Drug uptake (functional) | = 11 nmol/mg | Intracellular level of spermine in L1210 cells in the absence of DFMO at 25 uM | ChEMBL. | 16392808 |
Drug uptake (functional) | = 11 nmol/mg | Intracellular level of spermine in L1210 cells in the absence of DFMO at 25 uM | ChEMBL. | 16392808 |
Drug uptake (functional) | = 24 nmol/mg | Intracellular level of spermidine in L1210 cells in the absence of DFMO at 25 uM | ChEMBL. | 16392808 |
Drug uptake (functional) | = 24 nmol/mg | Intracellular level of spermidine in L1210 cells in the absence of DFMO at 25 uM | ChEMBL. | 16392808 |
IC50 (binding) | = 22 uM | Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesterase | ChEMBL. | 16392808 |
IC50 (binding) | = 22 uM | Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesterase | ChEMBL. | 16392808 |
IC50 (functional) | > 100 uM | Inhibition of cell growth in CHO-MG cells in the presence of DFMO | ChEMBL. | 16392808 |
Selectivity ratio (functional) | = 1 | Selectivity for uptake CHO cell line over CHO-MG cell line at 50 uM | ChEMBL. | 16392808 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.