Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | Glutamate NMDA receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.1308 | 1 | 0.5 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0538 | 0.397 | 0.397 |
Echinococcus multilocularis | protein dispatched 1 | 0.0538 | 0.397 | 0.397 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0538 | 0.397 | 0.397 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0614 | 0.4558 | 1 |
Echinococcus multilocularis | protein patched | 0.0538 | 0.397 | 0.397 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0614 | 0.4558 | 1 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.1308 | 1 | 0.5 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.1308 | 1 | 0.5 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0614 | 0.4558 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1308 | 1 | 1 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.1308 | 1 | 0.5 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.1308 | 1 | 1 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.1308 | 1 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0538 | 0.397 | 0.397 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.1308 | 1 | 1 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0538 | 0.397 | 0.397 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0538 | 0.397 | 0.397 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0614 | 0.4558 | 0.5 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.1308 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.