Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | histone deacetylase hda2 | 0.0488 | 0.4323 | 0.4304 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1114 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor co repressor related (ncor) | 0.0278 | 0.2421 | 0.2418 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0015 | 0.0033 | 0.0028 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Entamoeba histolytica | hypothetical protein | 0.0055 | 0.0399 | 0.0368 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase vps34-like | 0.0023 | 0.0108 | 0.0103 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0999 | 0.8958 | 0.8957 |
Echinococcus granulosus | macrophage colony stimulating factor 1 receptor | 0.0394 | 0.3468 | 0.3468 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0023 | 0.0108 | 0.0075 |
Toxoplasma gondii | histone deacetylase HDAC4 | 0.0665 | 0.5932 | 0.5919 |
Trichomonas vaginalis | brca1-associated protein, putative | 0.002 | 0.0073 | 0.0069 |
Plasmodium vivax | histone deacetylase, putative | 0.0999 | 0.8958 | 0.8954 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0239 | 0.2064 | 0.2064 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.007 | 0.0528 | 0.0524 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0488 | 0.4323 | 0.432 |
Trypanosoma cruzi | Zn-finger in ubiquitin-hydrolases and other protein, putative | 0.002 | 0.0073 | 0.0069 |
Loa Loa (eye worm) | BRCA1-associated protein 2 containing protein | 0.002 | 0.0073 | 0.0068 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0023 | 0.0108 | 0.0075 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0999 | 0.8958 | 0.8957 |
Brugia malayi | heat shock protein 90 | 0.0015 | 0.0033 | 0.0027 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1114 | 1 | 1 |
Loa Loa (eye worm) | ubiquitin carboxyl-terminal hydrolase | 0.002 | 0.0073 | 0.0068 |
Plasmodium falciparum | U4/U6.U5 tri-snRNP-associated protein 2, putative | 0.002 | 0.0073 | 0.0041 |
Echinococcus granulosus | heat shock protein 90 | 0.0012 | 0.0005 | 0.0005 |
Brugia malayi | Histone deacetylase family protein | 0.0999 | 0.8958 | 0.8957 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.002 | 0.0073 | 0.0069 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0488 | 0.4323 | 1 |
Trypanosoma cruzi | Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative | 0.002 | 0.0073 | 0.0069 |
Leishmania major | histone deacetylase, putative | 0.1114 | 1 | 1 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.002 | 0.0073 | 0.0068 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Echinococcus multilocularis | BRCA1 associated protein | 0.002 | 0.0073 | 0.0069 |
Echinococcus multilocularis | histone deacetylase 8 | 0.0488 | 0.4323 | 0.432 |
Brugia malayi | Histone deacetylase family protein | 0.0999 | 0.8958 | 0.8957 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.002 | 0.0073 | 0.0068 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.007 | 0.0528 | 0.0497 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0012 | 0.0005 | 0.5 |
Trypanosoma brucei | histone deacetylase 3 | 0.0999 | 0.8958 | 0.8954 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0021 | 0.0089 | 0.0084 |
Treponema pallidum | heat shock protein 90 | 0.0012 | 0.0005 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.0999 | 0.8958 | 0.8957 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.007 | 0.0528 | 0.0524 |
Schistosoma mansoni | ubiquitin-specific peptidase 5 (C19 family) | 0.002 | 0.0073 | 0.0041 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0015 | 0.0033 | 0.0028 |
Plasmodium vivax | ubiquitin carboxyl-terminal hydrolase 13, putative | 0.002 | 0.0073 | 0.0041 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0999 | 0.8958 | 0.8954 |
Echinococcus granulosus | histone deacetylase 6 | 0.1018 | 0.9135 | 0.9135 |
Trypanosoma brucei | Zn-finger in ubiquitin-hydrolases and other protein, putative | 0.002 | 0.0073 | 0.0041 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0048 | 0.033 | 0.0326 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0048 | 0.033 | 0.0326 |
Loa Loa (eye worm) | ubiquitin carboxyl-terminal hydrolase | 0.002 | 0.0073 | 0.0068 |
Plasmodium vivax | histone deacetylase 1, putative | 0.1114 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.002 | 0.0073 | 0.0069 |
Echinococcus granulosus | nuclear receptor co repressor related ncor | 0.0278 | 0.2421 | 0.2421 |
Toxoplasma gondii | Zn-finger in ubiquitin-hydrolases domain-containing protein | 0.002 | 0.0073 | 0.0041 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 22 | 0.002 | 0.0073 | 0.0069 |
Brugia malayi | Protein kinase domain containing protein | 0.0145 | 0.1215 | 0.1211 |
Giardia lamblia | Histone deacetylase | 0.1114 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.002 | 0.0073 | 0.0069 |
Echinococcus multilocularis | heat shock protein | 0.0015 | 0.0033 | 0.0028 |
Schistosoma mansoni | family C19 non-peptidase homologue (C19 family) | 0.002 | 0.0073 | 0.0041 |
Echinococcus granulosus | heat shock protein | 0.0015 | 0.0033 | 0.0033 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Trypanosoma brucei | histone deacetylase 2 | 0.0488 | 0.4323 | 0.4304 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1114 | 1 | 1 |
Trypanosoma brucei | histone deacetylase 1 | 0.1114 | 1 | 1 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0117 | 0.0956 | 0.0951 |
Loa Loa (eye worm) | CAMK/CAMKL/CHK1 protein kinase | 0.0145 | 0.1215 | 0.1211 |
Loa Loa (eye worm) | ubiquitin specific peptidase 39 | 0.002 | 0.0073 | 0.0068 |
Echinococcus granulosus | histone deacetylase 6 | 0.0999 | 0.8958 | 0.8958 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0031 | 0.0177 | 0.0144 |
Trichomonas vaginalis | phopsphatidylinositol 3-kinase, drosophila, putative | 0.007 | 0.0528 | 0.0524 |
Leishmania major | hypothetical protein, conserved | 0.002 | 0.0073 | 0.0069 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0023 | 0.0108 | 0.0103 |
Echinococcus granulosus | phosphatidylinositol 45 bisphosphate 3 kinase | 0.0131 | 0.1085 | 0.1085 |
Giardia lamblia | Phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.0034 | 0.0201 | 0.0196 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.1114 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1114 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 8 | 0.0488 | 0.4323 | 0.4323 |
Entamoeba histolytica | histone deacetylase, putative | 0.1114 | 1 | 1 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0999 | 0.8958 | 0.8954 |
Plasmodium vivax | U4/U6.U5 tri-snRNP-associated protein 2, putative | 0.002 | 0.0073 | 0.0041 |
Trypanosoma brucei | Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative | 0.002 | 0.0073 | 0.0041 |
Echinococcus granulosus | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0045 | 0.0306 | 0.0306 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0023 | 0.0108 | 0.0075 |
Giardia lamblia | Hypothetical protein | 0.002 | 0.0073 | 0.0069 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Plasmodium falciparum | histone deacetylase, putative | 0.0999 | 0.8958 | 0.8954 |
Toxoplasma gondii | UBA/TS-N domain-containing protein | 0.002 | 0.0073 | 0.0041 |
Trypanosoma brucei | histone deacetylase 4 | 0.0999 | 0.8958 | 0.8954 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.002 | 0.0073 | 0.0069 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 22 | 0.002 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.053 | 0.4709 | 0.4706 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0239 | 0.2064 | 0.206 |
Loa Loa (eye worm) | hypothetical protein | 0.1114 | 1 | 1 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 1, putative | 0.0068 | 0.051 | 0.0478 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0999 | 0.8958 | 0.8957 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0023 | 0.0108 | 0.0075 |
Toxoplasma gondii | ubiquitin specific protease 39 isoform 2, putative | 0.002 | 0.0073 | 0.0041 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1114 | 1 | 1 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0012 | 0.0005 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.002 | 0.0073 | 0.0041 |
Leishmania major | histone deacetylase, putative | 0.1114 | 1 | 1 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.002 | 0.0073 | 0.0069 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0999 | 0.8958 | 0.8957 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0999 | 0.8958 | 0.8957 |
Trichomonas vaginalis | BRCA1-associated protein, putative | 0.002 | 0.0073 | 0.0069 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit gamma, putative | 0.007 | 0.0528 | 0.0524 |
Brugia malayi | histone deacetylase 11 | 0.0665 | 0.5932 | 0.593 |
Schistosoma mansoni | histone deacetylase hda2 | 0.1018 | 0.9135 | 0.9132 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0012 | 0.0005 | 0.5 |
Echinococcus granulosus | BRCA1 associated protein | 0.002 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0119 | 0.0114 |
Trichomonas vaginalis | heat shock protein, putative | 0.0015 | 0.0033 | 0.0028 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1114 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Brugia malayi | Endoplasmin precursor | 0.0015 | 0.0033 | 0.0027 |
Echinococcus granulosus | histone deacetylase 6 | 0.0999 | 0.8958 | 0.8958 |
Trypanosoma brucei | histone deacetylase, putative | 0.0999 | 0.8958 | 0.8954 |
Echinococcus multilocularis | phosphatidylinositol 4,5 bisphosphate 3 kinase | 0.0131 | 0.1085 | 0.1081 |
Echinococcus multilocularis | histone deacetylase | 0.0999 | 0.8958 | 0.8957 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1114 | 1 | 1 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0023 | 0.0108 | 0.0103 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0023 | 0.0108 | 0.0103 |
Schistosoma mansoni | brca1-associated protein (brap2) | 0.002 | 0.0073 | 0.0041 |
Brugia malayi | phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative | 0.0061 | 0.0453 | 0.0448 |
Echinococcus granulosus | histone deacetylase 1 | 0.1114 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 3 | 0.1114 | 1 | 1 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase, putative | 0.0021 | 0.0089 | 0.0084 |
Plasmodium falciparum | histone deacetylase 1 | 0.1114 | 1 | 1 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.1114 | 1 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0015 | 0.0033 | 0.0028 |
Entamoeba histolytica | Sir2 family transcriptional regulator, putative | 0.002 | 0.0073 | 0.0041 |
Echinococcus multilocularis | histone deacetylase 1 | 0.1114 | 1 | 1 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 5 | 0.002 | 0.0073 | 0.0069 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0999 | 0.8958 | 0.8957 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 14 | 0.002 | 0.0073 | 0.0069 |
Plasmodium vivax | histone deacetylase, putative | 0.0665 | 0.5932 | 0.5919 |
Toxoplasma gondii | histone deacetylase HDAC5 | 0.0488 | 0.4323 | 0.4304 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.1114 | 1 | 1 |
Trypanosoma cruzi | Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative | 0.002 | 0.0073 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0488 | 0.4323 | 0.432 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.002 | 0.0073 | 0.0041 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Brugia malayi | Histone deacetylase 1 | 0.1114 | 1 | 1 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.002 | 0.0073 | 0.0041 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0015 | 0.0033 | 0.0028 |
Loa Loa (eye worm) | ubiquitin carboxyl-terminal hydrolase | 0.002 | 0.0073 | 0.0068 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0145 | 0.1215 | 0.1187 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.1114 | 1 | 1 |
Schistosoma mansoni | histone deacetylase | 0.1114 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.002 | 0.0073 | 0.0069 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.007 | 0.0528 | 0.0523 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1506 | 0.1501 |
Echinococcus granulosus | heat shock protein 90 | 0.0015 | 0.0033 | 0.0033 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0488 | 0.4323 | 0.432 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0045 | 0.0306 | 0.03 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Echinococcus multilocularis | heat shock protein 90 | 0.0015 | 0.0033 | 0.0028 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1114 | 1 | 1 |
Schistosoma mansoni | brca1-associated protein (brap2) | 0.002 | 0.0073 | 0.0041 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1114 | 1 | 1 |
Plasmodium falciparum | ubiquitin carboxyl-terminal hydrolase 13, putative | 0.002 | 0.0073 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0306 | 0.03 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0999 | 0.8958 | 0.8957 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0012 | 0.0005 | 0.0005 |
Echinococcus multilocularis | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0045 | 0.0306 | 0.0301 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0239 | 0.2064 | 0.2038 |
Echinococcus multilocularis | u4:u6.u5 tri snrnp associated protein 2 | 0.002 | 0.0073 | 0.0069 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.002 | 0.0073 | 0.0041 |
Echinococcus multilocularis | histone deacetylase 3 | 0.1114 | 1 | 1 |
Plasmodium falciparum | ubiquitin carboxyl-terminal hydrolase, putative | 0.002 | 0.0073 | 0.0041 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.002 | 0.0073 | 0.0069 |
Schistosoma mansoni | ubiquitin-specific peptidase 44 (C19 family) | 0.002 | 0.0073 | 0.0041 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0015 | 0.0033 | 0.0028 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Loa Loa (eye worm) | endoplasmin | 0.0015 | 0.0033 | 0.0027 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0665 | 0.5932 | 0.593 |
Echinococcus granulosus | endoplasmin | 0.0012 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0511 | 0.4531 | 0.4528 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.007 | 0.0528 | 0.0524 |
Echinococcus granulosus | histone deacetylase | 0.0999 | 0.8958 | 0.8958 |
Leishmania major | histone deacetylase, putative | 0.0999 | 0.8958 | 0.8957 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0023 | 0.0108 | 0.0102 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0015 | 0.0033 | 0.0027 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0131 | 0.1085 | 0.1056 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.002 | 0.0073 | 0.0069 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0999 | 0.8958 | 0.8954 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0012 | 0.0005 | 0.5 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase 5, putative | 0.002 | 0.0073 | 0.0041 |
Brugia malayi | BRCA1-associated protein 2 containing protein | 0.002 | 0.0073 | 0.0068 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0015 | 0.0033 | 0.0028 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.002 | 0.0073 | 0.0068 |
Echinococcus multilocularis | histone deacetylase 6 | 0.1018 | 0.9135 | 0.9135 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.1114 | 1 | 1 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0999 | 0.8958 | 0.8954 |
Giardia lamblia | Phosphoinositide-3-kinase, class 3 | 0.0016 | 0.0044 | 0.0039 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0488 | 0.4323 | 0.4304 |
Schistosoma mansoni | histone deacetylase | 0.1114 | 1 | 1 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.1114 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 7 | 0.0999 | 0.8958 | 0.8958 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.1114 | 1 | 1 |
Plasmodium falciparum | histone deacetylase 2 | 0.0999 | 0.8958 | 0.8954 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0055 | 0.0399 | 0.0368 |
Leishmania major | heat shock protein 83-1 | 0.0015 | 0.0033 | 0.0028 |
Echinococcus granulosus | u4:u6.u5 tri snrnp associated protein 2 | 0.002 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | histone deacetylase | 0.0999 | 0.8958 | 0.8957 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 18 nM | Antiviral activity against HIV1 V106A mutant using HeLa MAGI assay | ChEMBL. | 16420058 |
IC50 (functional) | = 93 nM | Antiviral activity against HIV1 K103N mutant using HeLa MAGI assay | ChEMBL. | 16420058 |
IC50 (functional) | = 290 nM | Antiviral activity against HIV1 Y181C mutant using HeLa MAGI assay | ChEMBL. | 16420058 |
Log IC50 (binding) | = 7.03 | Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assay | ChEMBL. | 18155520 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.