Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0041 | 0 | 0.5 | |
Plasmodium falciparum | apical sushi protein | 0.0041 | 0 | 0.5 |
Echinococcus multilocularis | irregular chiasm roughest protein immunoglobulin set domain containing protein | 0.0054 | 0.4651 | 1 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0054 | 0.4787 | 0.4787 |
Plasmodium vivax | apical sushi protein, putative | 0.0041 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.1629 | 0.1629 |
Onchocerca volvulus | 0.0041 | 0 | 0.5 | |
Onchocerca volvulus | 0.0041 | 0 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.4651 | 1 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0069 | 1 | 1 |
Onchocerca volvulus | 0.0041 | 0 | 0.5 | |
Echinococcus multilocularis | conserved hypothetical protein | 0.0054 | 0.4651 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.4787 | 0.4787 |
Toxoplasma gondii | rhoptry neck protein RON1 | 0.0041 | 0 | 0.5 |
Onchocerca volvulus | 0.0041 | 0 | 0.5 | |
Onchocerca volvulus | 0.0041 | 0 | 0.5 | |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0069 | 1 | 1 |
Toxoplasma gondii | rhoptry neck protein RON9 | 0.0041 | 0 | 0.5 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0069 | 1 | 1 |
Onchocerca volvulus | 0.0041 | 0 | 0.5 | |
Echinococcus multilocularis | Immunoglobulin | 0.0054 | 0.4651 | 1 |
Brugia malayi | hypothetical protein | 0.0069 | 1 | 1 |
Echinococcus granulosus | irregular chiasm roughest protein | 0.0054 | 0.4651 | 1 |
Echinococcus granulosus | nephrin | 0.0054 | 0.4651 | 1 |
Onchocerca volvulus | 0.0041 | 0 | 0.5 | |
Onchocerca volvulus | 0.0041 | 0 | 0.5 | |
Echinococcus granulosus | nephrin | 0.0054 | 0.4651 | 1 |
Echinococcus granulosus | Immunoglobulin | 0.0054 | 0.4651 | 1 |
Echinococcus multilocularis | nephrin | 0.0054 | 0.4651 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.4651 | 1 |
Onchocerca volvulus | 0.0041 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Dose (functional) | 0 mg kg-1 | Beta adrenoreceptor blocking potency by inhibition of 50% of the tachycardia produced by a submaximal dose of the isoproterenol (0.2microg/kg, intravenously). | ChEMBL. | 6118435 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.