Detailed information for compound 371482

Basic information

Technical information
  • TDR Targets ID: 371482
  • Name: (2R)-N-[(2S)-1-[[2-[4-(diaminomethylideneamin o)phenyl]-1-diphenoxyphosphorylethyl]amino]-1 -oxopropan-2-yl]-3-hydroxy-2-(thiophen-2-ylsu lfonylamino)propanamide
  • MW: 714.749 | Formula: C31H35N6O8PS2
  • H donors: 6 H acceptors: 6 LogP: 3.03 Rotable bonds: 19
    Rule of 5 violations (Lipinski): 3
  • SMILES: OC[C@H](C(=O)N[C@H](C(=O)NC(P(=O)(Oc1ccccc1)Oc1ccccc1)Cc1ccc(cc1)NC(=N)N)C)NS(=O)(=O)c1cccs1
  • InChi: 1S/C31H35N6O8PS2/c1-21(34-30(40)26(20-38)37-48(42,43)28-13-8-18-47-28)29(39)36-27(19-22-14-16-23(17-15-22)35-31(32)33)46(41,44-24-9-4-2-5-10-24)45-25-11-6-3-7-12-25/h2-18,21,26-27,37-38H,19-20H2,1H3,(H,34,40)(H,36,39)(H4,32,33,35)/t21-,26+,27?/m0/s1
  • InChiKey: XYPIYAMNGMADEW-AIOJJWOTSA-N  

Network

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Synonyms

  • (2R)-N-[(1S)-2-[[1-diphenoxyphosphoryl-2-(4-guanidinophenyl)ethyl]amino]-1-methyl-2-oxo-ethyl]-3-hydroxy-2-(2-thienylsulfonylamino)propanamide
  • (2R)-N-[(1S)-2-[[1-diphenoxyphosphoryl-2-(4-guanidinophenyl)ethyl]amino]-1-methyl-2-oxoethyl]-3-hydroxy-2-(2-thienylsulfonylamino)propanamide
  • (2R)-N-[(2S)-1-[[2-[4-[bis(azanyl)methylideneamino]phenyl]-1-diphenoxyphosphoryl-ethyl]amino]-1-oxo-propan-2-yl]-3-hydroxy-2-(thiophen-2-ylsulfonylamino)propanamide
  • (2R)-N-[(1S)-2-[[1-diphenoxyphosphoryl-2-(4-guanidinophenyl)ethyl]amino]-2-keto-1-methyl-ethyl]-3-hydroxy-2-(2-thienylsulfonylamino)propionamide
  • (2R)-N-[(2S)-1-[[1-[bis(phenoxy)phosphoryl]-2-[4-(diaminomethylideneamino)phenyl]ethyl]amino]-1-oxopropan-2-yl]-3-hydroxy-2-(thiophen-2-ylsulfonylamino)propanamide
  • (2R)-N-[(1S)-2-[[1-[bis(phenoxy)phosphoryl]-2-(4-guanidinophenyl)ethyl]amino]-1-methyl-2-oxo-ethyl]-3-hydroxy-2-(2-thienylsulfonylamino)propanamide
  • (2R)-N-[(1S)-2-[[1-[bis(phenoxy)phosphoryl]-2-(4-guanidinophenyl)ethyl]amino]-1-methyl-2-oxoethyl]-3-hydroxy-2-(2-thienylsulfonylamino)propanamide
  • (2R)-N-[(1S)-2-[[1-[bis(phenoxy)phosphoryl]-2-(4-guanidinophenyl)ethyl]amino]-2-keto-1-methyl-ethyl]-3-hydroxy-2-(2-thienylsulfonylamino)propionamide
  • (2R)-N-[(2S)-1-[[1-[bis(phenoxy)phosphoryl]-2-[4-(diaminomethylideneamino)phenyl]ethyl]amino]-1-oxo-propan-2-yl]-3-hydroxy-2-(thiophen-2-ylsulfonylamino)propanamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens coagulation factor II (thrombin) Starlite/ChEMBL References
Homo sapiens plasminogen Starlite/ChEMBL References
Homo sapiens plasminogen activator, tissue Starlite/ChEMBL References
Homo sapiens plasminogen activator, urokinase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus Mastin plasminogen activator, urokinase 414 aa 340 aa 24.4 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi Kringle domain containing protein 0.0105 0.2802 0.2798
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0056 0.123 0.1968
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0173 0.4989 1
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0018 0.0014 0.0014
Entamoeba histolytica hypothetical protein 0.0092 0.2389 0.6931
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0121 0.3342 0.3338
Onchocerca volvulus 0.0162 0.466 0.8717
Echinococcus multilocularis N chimaerin 0.0018 0.0014 0.0018
Schistosoma mansoni tyrosine kinase 0.0061 0.1397 0.179
Loa Loa (eye worm) SRC-1 0.0058 0.1292 0.1292
Schistosoma mansoni tyrosine kinase 0.0093 0.244 0.3133
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0061 0.1397 0.1796
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0049 0.1014 0.1304
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.014 0.3941 0.5069
Plasmodium falciparum cysteine repeat modular protein 1 0.0105 0.2802 0.5
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0051 0.1085 0.1637
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0092 0.2389 0.6931
Echinococcus granulosus integrin alpha 3 0.0123 0.3395 0.4366
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.014 0.3941 0.5069
Brugia malayi protein-tyrosine kinase 0.0049 0.1014 0.1009
Echinococcus multilocularis dual specificity mitogen activated protein 0.0173 0.4989 0.6416
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0049 0.1014 0.1304
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0058 0.1292 0.1661
Echinococcus multilocularis growth factor receptor bound protein 2 0.0018 0.0006 0.0008
Brugia malayi Kelch motif family protein 0.005 0.1048 0.1043
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0058 0.1292 0.1661
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0058 0.1292 0.1661
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0112 0.3036 0.9555
Schistosoma mansoni tyrosine kinase 0.018 0.5232 0.6726
Echinococcus granulosus integrin alpha ps 0.0072 0.1754 0.2256
Loa Loa (eye worm) hypothetical protein 0.014 0.3941 0.3941
Schistosoma mansoni tyrosine kinase 0.0061 0.1397 0.179
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0018 0.0014 0.001
Trichomonas vaginalis STE family protein kinase 0.0173 0.4989 1
Leishmania major hypothetical protein, conserved 0.0105 0.2802 0.4496
Entamoeba histolytica protein kinase, putative 0.004 0.073 0.0193
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0183 0.531 0.531
Echinococcus granulosus insulin receptor 0.0061 0.1397 0.1796
Brugia malayi Tyrosine-protein kinase abl-1 0.0023 0.019 0.0184
Trypanosoma brucei developmentally regulated phosphoprotein 0.014 0.3941 0.7568
Echinococcus multilocularis 0.0054 0.1189 0.1529
Schistosoma mansoni integrin alpha-ps 0.0037 0.0647 0.0825
Schistosoma mansoni protein kinase 0.0173 0.4989 0.6413
Echinococcus granulosus N chimaerin 0.0018 0.0014 0.0018
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0115 0.3145 0.5826
Echinococcus multilocularis tyrosine protein kinase Abl 0.0023 0.019 0.0244
Echinococcus granulosus integrin beta 2 0.0244 0.7264 0.9342
Echinococcus granulosus tyrosine protein kinase Blk 0.0049 0.1014 0.1304
Loa Loa (eye worm) TK protein kinase 0.004 0.073 0.073
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0018 0.0014 0.0018
Echinococcus granulosus epidermal growth factor receptor 0.0099 0.2624 0.3375
Schistosoma mansoni hypothetical protein 0.0034 0.0551 0.0702
Loa Loa (eye worm) hypothetical protein 0.0034 0.0551 0.0551
Echinococcus granulosus tyrosine protein kinase HCK 0.004 0.073 0.0938
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0217 0.6405 0.8238
Trichomonas vaginalis STE family protein kinase 0.0173 0.4989 1
Schistosoma mansoni tyrosine kinase 0.0099 0.2624 0.337
Schistosoma mansoni tyrosine kinase 0.0099 0.2624 0.337
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.014 0.3941 0.7628
Loa Loa (eye worm) phosphatidylinositol 3 0.0035 0.0572 0.0572
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0217 0.6405 0.8236
Loa Loa (eye worm) hypothetical protein 0.0037 0.0647 0.0647
Schistosoma mansoni hypothetical protein 0.0105 0.2802 0.3599
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0058 0.1292 0.1661
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0115 0.3145 0.5826
Echinococcus multilocularis tyrosine protein kinase Blk 0.0049 0.1014 0.1304
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0039 0.0682 0.087
Echinococcus multilocularis integrin alpha ps 0.0034 0.0551 0.0709
Echinococcus multilocularis tyrosine protein kinase Srms 0.0049 0.1014 0.1304
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0049 0.1016 0.1005
Loa Loa (eye worm) integrin alpha pat-2 0.0247 0.7388 0.7388
Echinococcus granulosus c src tyrosine kinase 0.0023 0.019 0.0244
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0058 0.1292 0.1661
Echinococcus granulosus growth factor receptor bound protein 2 0.0018 0.0006 0.0008
Echinococcus granulosus dual specificity mitogen activated protein 0.0173 0.4989 0.6416
Loa Loa (eye worm) hypothetical protein 0.0075 0.1841 0.1841
Loa Loa (eye worm) TK/EGFR protein kinase 0.018 0.5232 0.5232
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0075 0.1841 0.2368
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.014 0.3941 0.5069
Echinococcus granulosus integrin alpha ps 0.0034 0.0551 0.0709
Toxoplasma gondii kringle domain-containing protein 0.0105 0.2802 1
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0099 0.2624 0.3375
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0006
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0058 0.1292 0.1661
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0115 0.3145 0.572
Echinococcus granulosus raf serine:threonine protein kinase 0.026 0.7776 1
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0079 0.1986 0.3028
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0058 0.1292 0.1661
Loa Loa (eye worm) TK/ROR protein kinase 0.0113 0.3076 0.3076
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0061 0.1397 0.1796
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0018 0.0014 0.001
Echinococcus multilocularis NCK adaptor protein 0.0018 0.0006 0.0008
Echinococcus granulosus tyrosine kinase 0.0049 0.1014 0.1304
Echinococcus multilocularis insulin receptor 0.0061 0.1397 0.1796
Schistosoma mansoni integrin beta subunit 0.0194 0.566 0.7277
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0173 0.4989 0.4986
Echinococcus granulosus tyrosine protein kinase Fyn 0.0058 0.1292 0.1661
Onchocerca volvulus Tyrosine kinase homolog 0.0171 0.4933 1
Leishmania major developmentally regulated phosphoprotein-like protein 0.014 0.3941 0.7363
Schistosoma mansoni integrin alpha 0.0161 0.4598 0.591
Schistosoma mansoni tyrosine kinase 0.0023 0.019 0.0236
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0105 0.2802 0.5
Echinococcus multilocularis integrin alpha ps 0.0072 0.1754 0.2256
Loa Loa (eye worm) phosphatidylinositol 3 0.0193 0.5649 0.5649
Trichomonas vaginalis STE family protein kinase 0.0173 0.4989 1
Echinococcus multilocularis integrin alpha ps 0.0072 0.1754 0.2256
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0039 0.0682 0.0677
Loa Loa (eye worm) hypothetical protein 0.005 0.1048 0.1048
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0102 0.2704 0.27
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0043 0.083 0.1068
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0023 0.019 0.0236
Schistosoma mansoni tyrosine kinase 0.0093 0.244 0.3133
Echinococcus multilocularis tissue type plasminogen activator 0.0105 0.2802 0.3604
Schistosoma mansoni tyrosine kinase 0.0023 0.019 0.0236
Echinococcus granulosus NCK adaptor protein 0.0018 0.0006 0.0008
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0149 0.423 0.423
Loa Loa (eye worm) hypothetical protein 0.0041 0.0748 0.0748
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0058 0.1292 0.1661
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0075 0.1841 0.2368
Brugia malayi SRC-1 0.0058 0.1292 0.1286
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0079 0.1986 0.3028
Loa Loa (eye worm) hypothetical protein 0.0089 0.2287 0.2287
Loa Loa (eye worm) integrin beta-2 0.0329 1 1
Echinococcus multilocularis tyrosine protein kinase HCK 0.004 0.073 0.0938
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0058 0.1292 0.1661
Echinococcus granulosus epidermal growth factor receptor 0.018 0.5232 0.6729
Loa Loa (eye worm) kelch domain-containing protein family protein 0.005 0.1048 0.1048
Echinococcus granulosus tyrosine protein kinase Fyn 0.0058 0.1292 0.1661
Echinococcus granulosus tyrosine protein kinase Src42A 0.0058 0.1292 0.1661
Loa Loa (eye worm) TK protein kinase 0.0049 0.1014 0.1014
Echinococcus granulosus tyrosine protein kinase Src42A 0.0043 0.083 0.1068
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0058 0.1292 0.1661
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0173 0.4989 1
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0039 0.0682 0.0248
Echinococcus granulosus tyrosine protein kinase Fyn 0.0058 0.1292 0.1661
Echinococcus multilocularis epidermal growth factor receptor 0.0099 0.2624 0.3375
Loa Loa (eye worm) TK/INSR protein kinase 0.0061 0.1397 0.1397
Loa Loa (eye worm) raf kinase 0.0254 0.7592 0.7592
Brugia malayi kinase, mitochondrial precursor 0.014 0.3941 0.3938
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0018 0.0006 0.0006
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0057 0.1266 0.1401
Echinococcus multilocularis epidermal growth factor receptor 0.018 0.5232 0.6729
Echinococcus granulosus tyrosine protein kinase Lyn 0.0059 0.1338 0.172
Brugia malayi RhoGAP domain containing protein 0.0018 0.0014 0.0008
Schistosoma mansoni tyrosine kinase 0.0093 0.244 0.3133
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0049 0.1016 0.0776
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0023 0.019 0.0244
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0115 0.3145 0.3141
Brugia malayi Protein kinase domain containing protein 0.0061 0.1397 0.1392
Schistosoma mansoni pyruvate dehydrogenase 0.0132 0.3691 0.4743
Echinococcus granulosus tissue type plasminogen activator 0.0105 0.2802 0.3604
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.2802 0.5049
Loa Loa (eye worm) hypothetical protein 0.0121 0.3342 0.3342
Schistosoma mansoni serine/threonine protein kinase 0.026 0.7776 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0183 0.531 0.5307
Loa Loa (eye worm) hypothetical protein 0.0105 0.2802 0.2802
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0058 0.1292 0.1661
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0173 0.4989 1
Giardia lamblia Kinase, STE STE20 0.0173 0.4989 1
Schistosoma mansoni pyruvate dehydrogenase 0.0132 0.3691 0.4743
Schistosoma mansoni tyrosine kinase 0.0058 0.1292 0.1655
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0018 0.0006 0.0006
Echinococcus granulosus tyrosine protein kinase Src64B 0.0058 0.1292 0.1661
Brugia malayi Furin-like cysteine rich region family protein 0.018 0.5232 0.5229
Brugia malayi Raf kinase 0.0251 0.749 0.7489
Brugia malayi Protein kinase domain containing protein 0.011 0.2986 0.2982
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0115 0.3145 1
Echinococcus multilocularis raf serine:threonine protein kinase 0.026 0.7776 1
Echinococcus multilocularis integrin beta 2 0.0244 0.7264 0.9342
Brugia malayi hypothetical protein 0.005 0.1048 0.1043
Schistosoma mansoni tyrosine kinase 0.0058 0.1292 0.1655
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0217 0.6405 0.8238
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0018 0.0014 0.0018
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0115 0.3145 0.572
Loa Loa (eye worm) hypothetical protein 0.0126 0.349 0.349
Schistosoma mansoni pyruvate dehydrogenase 0.014 0.3941 0.5065
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0023 0.019 0.0244
Echinococcus multilocularis c src tyrosine kinase 0.0023 0.019 0.0244
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0014 0.0008
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0173 0.4989 0.4989
Brugia malayi Integrin alpha pat-2 precursor 0.0161 0.4598 0.4594
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0075 0.1841 0.1836
Schistosoma mansoni vav2 0.0018 0.0014 0.001
Echinococcus multilocularis integrin alpha 3 0.0123 0.3395 0.4366
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0115 0.3145 0.572
Schistosoma mansoni integrin alpha-ps 0.0072 0.1754 0.225

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.5 nM Inhibition of human uPA ChEMBL. 16970403
IC50 (binding) = 1.5 nM Inhibition of human uPA ChEMBL. 16970403
IC50 (binding) = 0.098 uM Inhibition of bovine trypsin ChEMBL. 16970403
IC50 (binding) = 1.54 uM Inhibition of human plasmin ChEMBL. 16970403
IC50 (binding) = 1.54 uM Inhibition of human plasmin ChEMBL. 16970403
IC50 (binding) = 3.4 uM Inhibition of recombinant tPA ChEMBL. 16970403
IC50 (binding) = 3.4 uM Inhibition of recombinant tPA ChEMBL. 16970403
IC50 (binding) = 4.3 uM Inhibition of human thrombin ChEMBL. 16970403
IC50 (binding) = 4.3 uM Inhibition of human thrombin ChEMBL. 16970403
Inhibition (binding) = 68 % Inhibition of bovine F10a at 250 uM ChEMBL. 16970403
Inhibition (binding) = 68 % Inhibition of bovine F10a at 250 uM ChEMBL. 16970403
Selectivity index (binding) = 65 Selectivity index, IC50 for bovine trypsin/IC50 for human uPA ChEMBL. 16970403
Selectivity index (binding) = 1000 Selectivity index, IC50 for human plasmin/IC50 for human uPA ChEMBL. 16970403
Selectivity index (binding) = 2300 Selectivity index, IC50 for recombinant tPA/IC50 for human uPA ChEMBL. 16970403
Selectivity index (binding) = 2800 Selectivity index, IC50 for human thrombin/IC50 for human uPA ChEMBL. 16970403

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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