Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | dipeptidyl-peptidase 4 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | tagatose-6-phosphate kinase, putative | 0.0082 | 0 | 0.5 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0209 | 0.2006 | 0.2006 |
Trichomonas vaginalis | ribokinase, putative | 0.0082 | 0 | 0.5 |
Leishmania major | adenosine kinase, putative | 0.0717 | 1 | 1 |
Trichomonas vaginalis | ribokinase, putative | 0.0082 | 0 | 0.5 |
Entamoeba histolytica | fructokinase, putative | 0.0082 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0717 | 1 | 1 |
Trypanosoma brucei | adenosine kinase, putative | 0.0717 | 1 | 1 |
Entamoeba histolytica | kinase, PfkB family | 0.0082 | 0 | 0.5 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0209 | 0.2006 | 0.2302 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0209 | 0.2006 | 0.2006 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0209 | 0.2006 | 0.2006 |
Mycobacterium tuberculosis | Adenosine kinase | 0.0082 | 0 | 0.5 |
Mycobacterium leprae | Probable adenosine kinase adk | 0.0082 | 0 | 0.5 |
Schistosoma mansoni | adenosine kinase | 0.0717 | 1 | 1 |
Trypanosoma cruzi | adenosine kinase, putative | 0.0717 | 1 | 1 |
Schistosoma mansoni | adenosine kinase | 0.0717 | 1 | 1 |
Toxoplasma gondii | kinase, pfkB family protein | 0.0717 | 1 | 1 |
Entamoeba histolytica | Hypothetical protein T24C12.3, putative | 0.0082 | 0 | 0.5 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0209 | 0.2006 | 0.2006 |
Trypanosoma brucei | adenosine kinase, putative | 0.0717 | 1 | 1 |
Mycobacterium tuberculosis | Ribokinase RbsK | 0.0082 | 0 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0209 | 0.2006 | 0.2006 |
Giardia lamblia | Ribokinase | 0.0082 | 0 | 0.5 |
Entamoeba histolytica | ribokinase, putative | 0.0082 | 0 | 0.5 |
Mycobacterium tuberculosis | 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) | 0.0082 | 0 | 0.5 |
Mycobacterium ulcerans | carbohydrate kinase CbhK | 0.0082 | 0 | 0.5 |
Trichomonas vaginalis | ribokinase, putative | 0.0082 | 0 | 0.5 |
Echinococcus granulosus | adenosine kinase | 0.0717 | 1 | 1 |
Onchocerca volvulus | 0.0636 | 0.8714 | 1 | |
Mycobacterium ulcerans | fructokinase, PfkB | 0.0082 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0 | 0.5 |
Trypanosoma cruzi | adenosine kinase, putative | 0.0717 | 1 | 1 |
Echinococcus multilocularis | adenosine kinase | 0.0717 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.