Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Peroxidasin | 0.0051 | 0.1032 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0051 | 0.1032 | 1 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0019 | 0.0079 | 0.5 |
Schistosoma mansoni | rab6-interacting | 0.0019 | 0.0079 | 0.0065 |
Brugia malayi | Blistered cuticle protein 3 | 0.0051 | 0.1032 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0019 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 1 |
Onchocerca volvulus | 0.0019 | 0.0079 | 0.0767 | |
Brugia malayi | hypothetical protein | 0.0019 | 0.0079 | 0.0767 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 1 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0019 | 0.0079 | 0.0079 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0019 | 0.0079 | 0.0079 |
Onchocerca volvulus | 0.0051 | 0.1032 | 1 | |
Brugia malayi | Animal haem peroxidase family protein | 0.0051 | 0.1032 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0019 | 0.0079 | 0.0079 |
Schistosoma mansoni | lipoxygenase | 0.0114 | 0.2927 | 0.2983 |
Echinococcus granulosus | RUN | 0.0019 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0079 | 0.0767 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0349 | 0.9984 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0051 | 0.1032 | 1 |
Echinococcus multilocularis | RUN | 0.0019 | 0.0079 | 0.0079 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0079 | 0.0767 |
Onchocerca volvulus | Neurogenic locus notch homolog | 0.0017 | 0.0016 | 0.0153 |
Brugia malayi | Animal haem peroxidase family protein | 0.0051 | 0.1032 | 1 |
Schistosoma mansoni | lipoxygenase | 0.008 | 0.1898 | 0.1929 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0051 | 0.1032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 1 |
Loa Loa (eye worm) | doublecortin family protein | 0.0019 | 0.0079 | 0.0767 |
Onchocerca volvulus | Peroxidasin homolog | 0.0051 | 0.1032 | 1 |
Schistosoma mansoni | peroxidasin | 0.0051 | 0.1032 | 0.1041 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0051 | 0.1032 | 1 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0019 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 1 |
Echinococcus granulosus | peroxidasin | 0.0051 | 0.1032 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0079 | 0.0767 |
Schistosoma mansoni | loxhd1 | 0.0019 | 0.0079 | 0.0065 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0051 | 0.1032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0051 | 0.1032 | 1 |
Echinococcus multilocularis | ankyrin repeat protein | 0.0342 | 0.9775 | 0.9775 |
Onchocerca volvulus | 0.0051 | 0.1032 | 1 | |
Schistosoma mansoni | rab6-interacting | 0.0019 | 0.0079 | 0.0065 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0019 | 0.0079 | 0.5 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0114 | 0.2927 | 0.2927 |
Onchocerca volvulus | Dual oxidase homolog | 0.0051 | 0.1032 | 1 |
Schistosoma mansoni | polycystin 1-related | 0.0019 | 0.0079 | 0.0065 |
Brugia malayi | Animal haem peroxidase family protein | 0.0051 | 0.1032 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0051 | 0.1032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 1 |
Brugia malayi | Doublecortin family protein | 0.0019 | 0.0079 | 0.0767 |
Onchocerca volvulus | Peroxidasin homolog | 0.0051 | 0.1032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0051 | 0.1032 | 1 |
Echinococcus granulosus | ankyrin repeat protein | 0.0342 | 0.9775 | 0.9791 |
Onchocerca volvulus | 0.0051 | 0.1032 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0079 | 0.0065 |
Schistosoma mansoni | peroxidasin | 0.0051 | 0.1032 | 0.1041 |
Onchocerca volvulus | 0.0019 | 0.0079 | 0.0767 | |
Brugia malayi | hypothetical protein | 0.0051 | 0.1032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0051 | 0.1032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0051 | 0.1032 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0019 | 0.0079 | 0.0079 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0114 | 0.2927 | 0.2932 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 1 |
Schistosoma mansoni | transient receptor potential cation channel subfamily A member | 0.0342 | 0.9775 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0051 | 0.1032 | 0.1032 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Radioactivity (ADMET) | = 1.842 % | Percent injected radioactivity was determined in kidney after intravenous administration into the tail vein of male swiss albino mice after 60 min | ChEMBL. | 7143375 |
Radioactivity (ADMET) | = 1.842 % | Percent injected radioactivity was determined in kidney after intravenous administration into the tail vein of male swiss albino mice after 60 min | ChEMBL. | 7143375 |
Radioactivity (ADMET) | = 4.406 % | Percent injected radioactivity was determined in blood after intravenous administration into the tail vein of male swiss albino mice after 60 min | ChEMBL. | 7143375 |
Radioactivity (ADMET) | = 4.41 % | Percent injected radioactivity was determined in blood after intravenous administration into the tail vein of male swiss albino mice after 60 min | ChEMBL. | 7143375 |
Radioactivity (ADMET) | = 5.254 % | Percent injected radioactivity was determined in muscle after intravenous administration into the tail vein of male swiss albino mice after 60 min | ChEMBL. | 7143375 |
Radioactivity (ADMET) | = 5.254 % | Percent injected radioactivity was determined in muscle after intravenous administration into the tail vein of male swiss albino mice after 60 min | ChEMBL. | 7143375 |
Radioactivity (ADMET) | = 9.736 % | Percent injected radioactivity was determined in urine after intravenous administration into the tail vein of male swiss albino mice after 60 min | ChEMBL. | 7143375 |
Radioactivity (ADMET) | = 9.74 % | Percent injected radioactivity was determined in urine after intravenous administration into the tail vein of male swiss albino mice after 60 min | ChEMBL. | 7143375 |
Radioactivity (ADMET) | = 22.748 % | Percent injected radioactivity was determined in liver and gallbladder after intravenous administration into the tail vein of male swiss albino mice after 60 min | ChEMBL. | 7143375 |
Radioactivity (ADMET) | = 22.748 % | Percent injected radioactivity was determined in liver and gallbladder after intravenous administration into the tail vein of male swiss albino mice after 60 min | ChEMBL. | 7143375 |
Radioactivity (ADMET) | = 51.3 % | Percent injected radioactivity was determined in intestine after intravenous administration into the tail vein of male swiss albino mice, after 60 min | ChEMBL. | 7143375 |
Radioactivity (ADMET) | = 51.3 % | Percent injected radioactivity was determined in intestine after intravenous administration into the tail vein of male swiss albino mice, after 60 min | ChEMBL. | 7143375 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.