Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0176 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0176 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0176 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0176 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0065 | 0.2232 | 0.2232 |
Echinococcus granulosus | cathepsin l1 | 0.0041 | 0.0582 | 0.0582 |
Echinococcus multilocularis | cathepsin b | 0.0176 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0059 | 0.1828 | 0.1323 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Onchocerca volvulus | Cathepsin L homolog | 0.0059 | 0.1828 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0059 | 0.1828 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Onchocerca volvulus | 0.0059 | 0.1828 | 1 | |
Toxoplasma gondii | cathepsin B | 0.0065 | 0.2232 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0176 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0176 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.1828 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.1828 | 0.8189 |
Loa Loa (eye worm) | hypothetical protein | 0.0176 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.1828 | 0.1323 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0059 | 0.1828 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.1828 | 0.8189 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0059 | 0.1828 | 0.1323 |
Brugia malayi | Cathepsin L-like precursor | 0.0041 | 0.0582 | 0.0582 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.1828 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0041 | 0.0582 | 0.2606 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0176 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Onchocerca volvulus | 0.0059 | 0.1828 | 1 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0059 | 0.1828 | 0.1828 |
Giardia lamblia | Cathepsin B precursor | 0.0065 | 0.2232 | 0.5 |
Onchocerca volvulus | 0.0059 | 0.1828 | 1 | |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0041 | 0.0582 | 0.0582 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0059 | 0.1828 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0059 | 0.1828 | 0.1828 |
Brugia malayi | Cathepsin L-like precursor | 0.0041 | 0.0582 | 0.0582 |
Brugia malayi | Cathepsin L-like precursor | 0.0059 | 0.1828 | 0.1828 |
Echinococcus multilocularis | cysteine protease | 0.0059 | 0.1828 | 0.1828 |
Giardia lamblia | Cathepsin B precursor | 0.0065 | 0.2232 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0059 | 0.1828 | 0.1828 |
Onchocerca volvulus | Cathepsin L homolog | 0.0059 | 0.1828 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0059 | 0.1828 | 0.1828 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.1828 | 0.8189 |
Brugia malayi | Cathepsin L-like precursor | 0.0059 | 0.1828 | 0.1828 |
Onchocerca volvulus | 0.0059 | 0.1828 | 1 | |
Plasmodium vivax | vivapain-2 | 0.0059 | 0.1828 | 1 |
Plasmodium vivax | vivapain-2 | 0.0059 | 0.1828 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0041 | 0.0582 | 0.0582 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.1828 | 0.8189 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0059 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0059 | 0.1828 | 0.1828 |
Brugia malayi | Cathepsin L-like precursor | 0.0059 | 0.1828 | 0.1828 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.1828 | 0.8189 |
Entamoeba histolytica | cysteine protease, putative | 0.0059 | 0.1828 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0065 | 0.2232 | 1 |
Onchocerca volvulus | 0.0059 | 0.1828 | 1 | |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0059 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0041 | 0.0582 | 0.2606 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0059 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Onchocerca volvulus | Cathepsin F homolog | 0.0059 | 0.1828 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0059 | 0.1828 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0065 | 0.2232 | 0.2232 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0059 | 0.1828 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Brugia malayi | Cathepsin L-like precursor | 0.0059 | 0.1828 | 0.1828 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0059 | 0.1828 | 0.1828 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0059 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0041 | 0.0582 | 0.3182 |
Echinococcus granulosus | cathepsin b | 0.0176 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Loa Loa (eye worm) | cathepsin B | 0.0065 | 0.2232 | 0.1752 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0059 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0059 | 0.1828 | 0.1828 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0059 | 0.1828 | 0.1828 |
Loa Loa (eye worm) | cysteine protease | 0.0059 | 0.1828 | 0.1323 |
Onchocerca volvulus | 0.0059 | 0.1828 | 1 | |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0041 | 0.0582 | 0.0582 |
Loa Loa (eye worm) | ctsf protein | 0.0059 | 0.1828 | 0.1323 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0059 | 0.1828 | 0.1828 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0059 | 0.1828 | 0.1828 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.1828 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Brugia malayi | cathepsin L-like precursor | 0.0041 | 0.0582 | 0.0582 |
Echinococcus multilocularis | cysteine protease | 0.0059 | 0.1828 | 0.1828 |
Giardia lamblia | Cathepsin B precursor | 0.0065 | 0.2232 | 0.5 |
Onchocerca volvulus | 0.0059 | 0.1828 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.1828 | 0.8189 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0065 | 0.2232 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0059 | 0.1828 | 0.1828 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0059 | 0.1828 | 0.1828 |
Loa Loa (eye worm) | fibroinase | 0.0059 | 0.1828 | 0.1323 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0065 | 0.2232 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.