Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | nuclear hormone receptor | 0.0077 | 0.3428 | 0.3428 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0162 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | neuropeptide receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | ecdysone receptor | 0.0077 | 0.3428 | 0.3428 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0162 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0077 | 0.3428 | 0.3428 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0162 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0162 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0086 | 0.4131 | 0.4131 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0162 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.3428 | 0.3428 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0162 | 1 | 1 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0077 | 0.3428 | 0.3428 |
Echinococcus granulosus | neuropeptide s receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0086 | 0.4131 | 0.4131 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.3428 | 0.3428 |
Brugia malayi | follicle stimulating hormone receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 1 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | neuropeptide receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | amine GPCR | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.3428 | 0.3428 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0162 | 1 | 1 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Onchocerca volvulus | 0.0162 | 1 | 1 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.3428 | 0.3428 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0077 | 0.3428 | 0.3428 |
Brugia malayi | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | neuropeptide receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | G-protein coupled receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.011 | 0.5984 | 0.5984 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | conserved hypotetical protein | 0.0077 | 0.3428 | 0.3428 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0162 | 1 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0162 | 1 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0086 | 0.4131 | 0.4131 |
Schistosoma mansoni | amine GPCR | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0162 | 1 | 1 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | g protein coupled receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | G protein-coupled receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0162 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0162 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0162 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0077 | 0.3428 | 0.3428 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0162 | 1 | 1 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | histamine h1 receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | hypothetical protein | 0.0077 | 0.3428 | 0.3428 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | sulfakinin receptor protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.4131 | 0.4131 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | fmrfamide receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Echinococcus multilocularis | allatostatin A receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | biogenic amine receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.3428 | 0.3428 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0162 | 1 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0162 | 1 | 1 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0161 | 0.9852 | 0.9852 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Loa Loa (eye worm) | steroid hormone receptor | 0.0162 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0086 | 0.4131 | 0.4131 |
Schistosoma mansoni | amine GPCR | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0161 | 0.9852 | 0.9852 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0162 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0162 | 1 | 1 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0161 | 0.9852 | 0.9775 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0162 | 1 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0077 | 0.3428 | 0.3428 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Echinococcus multilocularis | fmrfamide receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | RE15519p | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | nuclear hormone receptor | 0.0162 | 1 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | g-protein coupled receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.3428 | 0.3428 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0162 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0162 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0077 | 0.3428 | 0.3428 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0162 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0162 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | nuclear receptor | 0.0077 | 0.3428 | 0.3428 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Dopamine receptor protein 1 | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | neuropeptide receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0077 | 0.3428 | 0.3428 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | nuclear hormone receptor | 0.0077 | 0.3428 | 0.3428 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Serotonin receptor | 0.0161 | 0.9852 | 0.9852 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0162 | 1 | 1 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0086 | 0.4131 | 0.4131 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.3428 | 0.3428 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0077 | 0.3428 | 0.3428 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | myosin xvIII | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | voltage-gated potassium channel | 0.012 | 0.6758 | 0.6758 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | voltage-gated potassium channel | 0.012 | 0.6758 | 0.6758 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.3428 | 0.3428 |
Schistosoma mansoni | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0162 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0162 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0077 | 0.3428 | 0.3428 |
Brugia malayi | neuropeptide F receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | hypothetical protein | 0.0086 | 0.4131 | 0.4131 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | nuclear receptor NHR-88 | 0.0162 | 1 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | biogenic amine receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.3428 | 0.3428 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | serotonin receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | g protein coupled receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.4131 | 0.4131 |
Brugia malayi | nuclear receptor NHR-67 | 0.0077 | 0.3428 | 0.3428 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | sex peptide receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Serotonin receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0077 | 0.3428 | 0.3428 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0162 | 1 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.4871 | 0.4871 |
Brugia malayi | nuclear receptor RXR | 0.0077 | 0.3428 | 0.3428 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.011 | 0.5984 | 0.5984 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.3428 | 0.3428 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 1 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | adenoreceptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | coup transcription factor | 0.0162 | 1 | 1 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0162 | 1 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Echinococcus granulosus | sex peptide receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0077 | 0.3428 | 0.3428 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.3428 | 0.3428 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0077 | 0.3428 | 0.3428 |
Echinococcus granulosus | somatostatin receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0162 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | amine GPCR | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0162 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0077 | 0.3428 | 0.3428 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | amine GPCR | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0077 | 0.3428 | 0.3428 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | nuclear receptor | 0.0077 | 0.3428 | 0.3428 |
Brugia malayi | nuclear receptor NHR-88 | 0.0077 | 0.3428 | 0.3428 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0162 | 1 | 1 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | opsin-like receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0162 | 1 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0086 | 0.4131 | 0.4131 |
Echinococcus granulosus | g protein coupled receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Dopamine receptor protein 2 | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0077 | 0.3428 | 0.3428 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | allatostatin A receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0162 | 1 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | g protein coupled receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0162 | 1 | 1 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Echinococcus granulosus | neuropeptides capa receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | FTZ F1 alpha | 0.0162 | 1 | 1 |
Brugia malayi | ORL1-like opioid receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | biogenic amine receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | GnHR receptor homolog | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | somatostatin receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | neuropeptide receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0162 | 1 | 1 |
Brugia malayi | putative neuropeptide receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.011 | 0.5984 | 0.5984 |
Brugia malayi | Dopamine receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | neuropeptide receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.4131 | 0.4131 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.3428 | 0.3428 |
Echinococcus granulosus | fmrfamide receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0162 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0161 | 0.9852 | 0.9852 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0162 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0162 | 1 | 1 |
Brugia malayi | Melatonin receptor type 1A | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0162 | 1 | 1 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0162 | 1 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | orexin receptor type 2 | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.4131 | 0.4131 |
Schistosoma mansoni | opsin-like receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0077 | 0.3428 | 0.3428 |
Schistosoma mansoni | nuclear hormone receptor | 0.0162 | 1 | 1 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | thyroid hormone receptor | 0.0162 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.011 | 0.5984 | 0.5984 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0162 | 1 | 1 |
Onchocerca volvulus | 0.0161 | 0.9852 | 0.9775 | |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0162 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.4131 | 0.4131 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0162 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0086 | 0.4131 | 0.4131 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0077 | 0.3428 | 0.3428 |
Brugia malayi | AKH receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0077 | 0.3428 | 0.3428 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 1 | 1 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0162 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0162 | 1 | 1 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0162 | 1 | 1 |
Brugia malayi | tailless protein | 0.0077 | 0.3428 | 0.3428 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0162 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0162 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0086 | 0.4131 | 0.4131 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | larval opioid receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0077 | 0.3428 | 0.3428 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0162 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0162 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0077 | 0.3428 | 0.3428 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0077 | 0.3428 | 0.3428 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0077 | 0.3428 | 0.3428 |
Echinococcus multilocularis | serotonin receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | DR-78 | 0.0077 | 0.3428 | 0.3428 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0077 | 0.3428 | 0.3428 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.3428 | 0.3428 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0162 | 1 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | nuclear receptor RXR | 0.0086 | 0.4131 | 0.4131 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | neuropeptide receptor | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0162 | 1 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0103 | 0.543 | 0.5 |
Brugia malayi | neuropeptide F receptor | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0077 | 0.3428 | 0.3428 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0103 | 0.543 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0162 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0161 | 0.9852 | 0.9852 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0161 | 0.9852 | 0.9775 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0161 | 0.9852 | 0.9852 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0161 | 0.9852 | 0.9852 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | thyroid hormone receptor | 0.0162 | 1 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0077 | 0.3428 | 0.3428 |
Schistosoma mansoni | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0077 | 0.3428 | 0.3428 |
Schistosoma mansoni | nuclear hormone receptor | 0.0077 | 0.3428 | 0.3428 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.9852 | 0.9852 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0161 | 0.9852 | 0.9852 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | = 7.98 uM | Effective concentration required for the lysis of Trypanosoma cruzi trypomastigotes in blood stream after 24 hours of treatment | ChEMBL. | 15324878 |
IC50 (binding) | = 23.16 nM | Inhibition of Peptidyl-prolyl cis-trans isomerase Trypanosoma cruzi cyclophilin (CL Brener strain, p19) | ChEMBL. | 15324878 |
IC50 (functional) | = 10.55 uM | Compound was tested for the inhibition of Trypanosoma cruzi epimastigote growth after 72 hours of treatment | ChEMBL. | 15324878 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.